Pdss1 - prenyl (solanesyl) diphosphate synthase, subunit 1 Gene

Also Known as TPT; Tprt; TPT 1; mDLP1; mSPS1; 2610203G20Rik; 2700031G06Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 56075

Summary

Enables protein heterodimerization activity. Contributes to trans-hexaprenyltranstransferase activity and trans-octaprenyltranstransferase activity. Involved in isoprenoid biosynthetic process and ubiquinone biosynthetic process. Located in mitochondrion. Part of transferase complex. Human ortholog(s) of this gene implicated in primary coenzyme Q10 deficiency 2. Orthologous to human PDSS1 (decaprenyl diphosphate synthase subunit 1). [provided by Alliance of Genome Resources, Apr 2022]

Pdss1 Products (2)

mRNA Protein Name
NM_001355467.2 NP_001342396.1 all trans-polyprenyl-diphosphate synthase PDSS1 isoform 2
NM_019501.4 NP_062374.2 all trans-polyprenyl-diphosphate synthase PDSS1 isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
contributes to all-trans-nonaprenyl-diphosphate synthase (geranyl-diphosphate specific) activity IDA
IDA: Inferred from direct assay
16262699 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
16262699 MGI
enables protein heterodimerization activity IDA
IDA: Inferred from direct assay
16262699 MGI
Biological Process GO Annotation Evidence References Source
involved in isoprenoid biosynthetic process IDA
IDA: Inferred from direct assay
16262699 MGI
involved in ubiquinone biosynthetic process IDA
IDA: Inferred from direct assay
16262699 MGI
Cellular Component GO Annotation Evidence References Source
part of heterotetrameric polyprenyl diphosphate synthase complex IDA
IDA: Inferred from direct assay
16262699 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

all trans-polyprenyl-diphosphate synthase PDSS1

decaprenyl-diphosphate synthase subunit 1

  • all-trans-decaprenyl-diphosphate synthase subunit 1

  • decaprenyl pyrophosphate synthase subunit 1

  • decaprenyl pyrophosphate synthetase subunit 1

  • solanesyl-diphosphate synthase subunit 1

  • subunit 1 of solanesyl diphosphate synthase

  • trans-prenyltransferase

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS10293 PDSS1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22714 Pdss1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS29228 Pdss1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Pdss1 NCBI NCBI:23590