1. Gene
  2. LTB4R2 - leukotriene B4 receptor 2 Gene

LTB4R2 - leukotriene B4 receptor 2 Gene

Homo sapiens

Also known as BLT2; NOP9; BLTR2; JULF2; KPG_004; LTB4-R2; LTB4-R 2

Gene ID: 56413 | Gene type: protein coding

About LTB4R2

Cytogenetic location: 14q12 Genomic coordinates (GRCh38): 14:24,310,140-24,312,038 (from NCBI)

This gene has 5 transcripts (splice variants), 1 gene allele, 238 orthologues and 17 paralogues. Broad expression in skin (RPKM 12.7), spleen (RPKM 9.3) and 21 other tissues.

Summary

Predicted to enable G protein-coupled peptide receptor activity and leukotriene B4 receptor activity. Predicted to be involved in inflammatory response and neuropeptide signaling pathway. Predicted to act upstream of or within keratinocyte migration and signal transduction. Located in nucleoplasm and plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

LTB4R2 Products(2)

mRNA Protein Name
NM_001164692.3 NP_001158164.1 leukotriene B4 receptor 2
NM_019839.5 NP_062813.2 leukotriene B4 receptor 2
Protein Preferred Names Protein Names

leukotriene B4 receptor 2

LTB4 receptor JULF2

Related Diseases

Diseases Alias
Psoriasis 5

PSORS5

Psoriasis Susceptibility 5

Psoriasis 5, Susceptibility To

Asthma

Chronic Obstructive Asthma

Asthma, Diminished Response To Antileukotriene Treatment In

Bronchial Hyperreactivity

Asthma, Susceptibility To

Asthma, Bronchial

Asthma, Protection Against

Asthma, Nocturnal, Susceptibility To

Nocturnal Asthma

Asthma-Related Traits

Asthma-Related Traits, Susceptibility To

Asthma, Nocturnal

Chronic Obstructive Asthma With Acute Exacerbation

Chronic Obstructive Asthma With Status Asthmaticus

Exercise Induced Asthma

Exercise-Induced Asthma

Bronchial Asthma

Asthma, Exercise-Induced

Idiosyncratic Asthma

Unspecified Asthma With Acute Exacerbation

Asthma, Unspecified, With Stated Status Asthmaticus

Status Asthmaticus Nos

Acute Severe Asthma

Acute Severe Bronchial Asthma

Status Asthma

Status Post Asthmaticus

Persistent Mild Asthma
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Orthologs Information

Species Symbol Source ID
Bos taurus LTB4R2 VGNC VGNC:31070
Mus musculus LTB4R2 MGD MGI:1888501
Rattus norvegicus LTB4R2 RGD RGD:621029
Macaca mulatta LTB4R2 VGNC VGNC:74314