Actl6a - actin-like 6A Gene

Also Known as ARP4; Actl6; Baf53a; 2810432C06Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 56456

Summary

Enables chromatin binding activity. Involved in nervous system development. Acts upstream of or within blastocyst formation and chromatin remodeling. Located in nucleus. Part of SWI/SNF complex and npBAF complex. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; lung; and nose. Orthologous to human ACTL6A (actin like 6A). [provided by Alliance of Genome Resources, Apr 2022]

Actl6a Products (1)

mRNA Protein Name
NM_019673.2 NP_062647.2 actin-like protein 6A

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables chromatin binding IDA
IDA: Inferred from direct assay
9845365 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
17640523 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within blastocyst formation IMP
IMP: Inferred from mutant phenotype
27869233 MGI
acts upstream of or within chromatin remodeling IDA
IDA: Inferred from direct assay
9845365 MGI
involved in nervous system development IMP
IMP: Inferred from mutant phenotype
17640523 MGI
involved in positive regulation of DNA repair IDA
IDA: Inferred from direct assay
23979016 MGI
involved in positive regulation of telomere maintenance in response to DNA damage IMP
IMP: Inferred from mutant phenotype
23979016 MGI
involved in regulation of DNA repair IDA
IDA: Inferred from direct assay
23979016 MGI
involved in regulation of embryonic development IMP
IMP: Inferred from mutant phenotype
23979016 MGI
involved in telomere maintenance IMP
IMP: Inferred from mutant phenotype
23979016 MGI
Cellular Component GO Annotation Evidence References Source
part of SWI/SNF complex IDA
IDA: Inferred from direct assay
29374058 MGI
part of SWI/SNF superfamily-type complex IDA
IDA: Inferred from direct assay
24335282 MGI
part of npBAF complex IDA
IDA: Inferred from direct assay
17640523 MGI
located in nucleus IDA
IDA: Inferred from direct assay
12437990 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

actin-like protein 6A

  • 53 kDa BRG1-associated factor A

  • BRG1-associated factor 53A

  • BRG1/brm-associated factor 53A

  • actin-like 6

  • actin-related protein Baf53a

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS00220 ACTL6A Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21812 Actl6a Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28328 Actl6a Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Actl6a NCBI NCBI:86