Mlst8 - MTOR associated protein, LST8 homolog (S. cerevisiae) Gene

Also Known as Gbl; 0610033N12Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 56716

Summary

Predicted to enable protein serine/threonine kinase activator activity. Acts upstream of or within positive regulation of actin filament polymerization; positive regulation of peptidyl-tyrosine phosphorylation; and regulation of GTPase activity. Part of TORC1 complex. Is expressed in central nervous system and retina. Orthologous to human MLST8 (mTOR associated protein, LST8 homolog). [provided by Alliance of Genome Resources, Apr 2022]

Mlst8 Products (4)

mRNA Protein Name
NM_001252463.1 NP_001239392.1 target of rapamycin complex subunit LST8 isoform 1
NM_001252464.1 NP_001239393.1 target of rapamycin complex subunit LST8 isoform 1
NM_001252465.1 NP_001239394.1 target of rapamycin complex subunit LST8 isoform 2
NM_019988.5 NP_064372.2 target of rapamycin complex subunit LST8 isoform 1

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
acts upstream of or within positive regulation of actin filament polymerization IMP
IMP: Inferred from mutant phenotype
15467718 MGI
acts upstream of or within positive regulation of peptidyl-tyrosine phosphorylation IMP
IMP: Inferred from mutant phenotype
15467718 MGI
acts upstream of or within regulation of GTPase activity IMP
IMP: Inferred from mutant phenotype
15467718 MGI
Cellular Component GO Annotation Evidence References Source
part of TORC1 complex IDA
IDA: Inferred from direct assay
12718876 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

target of rapamycin complex subunit LST8

  • TORC subunit LST8

  • mammalian lethal with SEC13 protein 8

  • protein GbetaL

  • transducin (beta)-like 4

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS08502 MLST8 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22642 Mlst8 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS29157 Mlst8 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Mlst8 NCBI NCBI:64223