2. Gene
  3. NCOA5 - nuclear receptor coactivator 5 Gene

NCOA5 - nuclear receptor coactivator 5 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as CIA; bA465L10.6

Gene ID: 57727 | Gene type: protein coding

About NCOA5

Cytogenetic location: 20q13.12 Genomic coordinates (GRCh38): 20:46,060,991-46,089,962 (from NCBI)

This gene has 2 transcripts (splice variants) and 202 orthologues. Ubiquitous expression in testis (RPKM 19.7), ovary (RPKM 15.7) and 25 other tissues.

Summary

This gene encodes a coregulator for the alpha and beta estrogen receptors and the orphan nuclear receptor NR1D2. The protein localizes to the nucleus, and is thought to have both coactivator and corepressor functions. Its interaction with nuclear receptors is independent of the AF2 domain on the receptors, which is known to regulate interaction with other coreceptors. Several alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2017]

NCOA5 Products(5)

mRNA Protein Name
NM_001348148.2 NP_001335077.1 nuclear receptor coactivator 5 isoform 2
NM_001348149.2 NP_001335078.1 nuclear receptor coactivator 5 isoform 3
NM_001348150.2 NP_001335079.1 nuclear receptor coactivator 5 isoform 4
NM_001348151.2 NP_001335080.1 nuclear receptor coactivator 5 isoform 5
NM_020967.3 NP_066018.1 nuclear receptor coactivator 5 isoform 1
Protein Preferred Names Protein Names

nuclear receptor coactivator 5

NCoA-5

Related Diseases

Diseases Alias
Night Blindness, Congenital Stationary, Type 1d

Congenital Stationary Night Blindness 1d

CSNB1D

Csnb, Complete, Autosomal Recessive

Night Blindness, Congenital Stationary , 1d, Autosomal Recessive

Congenital Stationary Night Blindness 1d Autosomal Recessive

Night Blindness, Congenital Stationary, 1d

Complete Autosomal Recessive Csnb

Blindness, Night, Stationary, Congenital, Type 1d
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS09093 NCOA5 Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus NCOA5 VGNC VGNC:31923
Macaca mulatta NCOA5 VGNC VGNC:74966
Felis catus NCOA5 VGNC VGNC:63741
Canis familiaris NCOA5 VGNC VGNC:43662
Rattus norvegicus NCOA5 RGD RGD:1307702
Mus musculus NCOA5 MGD MGI:2385165