2. Gene
  3. RABGGTA - Rab geranylgeranyltransferase subunit alpha Gene

RABGGTA - Rab geranylgeranyltransferase subunit alpha Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as PTAR3

Gene ID: 5875 | Gene type: protein coding

About RABGGTA

Cytogenetic location: 14q12 Genomic coordinates (GRCh38): 14:24,265,538-24,271,627 (from NCBI)

This gene has 21 transcripts (splice variants), 1 gene allele, 181 orthologues and 2 paralogues. Ubiquitous expression in esophagus (RPKM 19.5), lung (RPKM 8.4) and 25 other tissues.

Summary

Predicted to enable small GTPase binding activity. Predicted to contribute to Rab geranylgeranyltransferase activity. Predicted to be involved in protein geranylgeranylation. Located in nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]

RABGGTA Products(2)

mRNA Protein Name
NM_004581.5 NP_004572.3 geranylgeranyl transferase type-2 subunit alpha
NM_182836.3 NP_878256.1 geranylgeranyl transferase type-2 subunit alpha

RABGGTA Protein Structure

PPTA

PPTA: Protein prenyltransferase alpha subunit repeat (49 - 77)

PPTA

PPTA: Protein prenyltransferase alpha subunit repeat (92 - 121)

PPTA

PPTA: Protein prenyltransferase alpha subunit repeat (127 - 154)

PPTA

PPTA: Protein prenyltransferase alpha subunit repeat (162 - 192)

PPTA

PPTA: Protein prenyltransferase alpha subunit repeat (210 - 238)

RabGGT_insert

RabGGT_insert: Rab geranylgeranyl transferase alpha-subunit, insert domain (243 - 345)

LRR_1

LRR_1: Leucine Rich Repeat (466 - 484)

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  • 567 a.a.
Protein Preferred Names Protein Names

geranylgeranyl transferase type-2 subunit alpha

Rab GG transferase alpha

Related Diseases

Diseases Alias
Choroideremia

CHM

Tcd

Progressive Tapetochoroidal Dystrophy

Choroidal Sclerosis

Tapetochoroidal Dystrophy, Progressive

Progressive Choroidal Atrophy

Tapetochoroidal Dystrophy
Hermansky-Pudlak Syndrome

Hps

Albinism With Hemorrhagic Diathesis And Pigmented Reticuloendothelial Cells

Hermanski-Pudlak Syndrome

Hermansky Pudlak Syndrome

Platelet Storage Pool Deficiency
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS11587 RABGGTA Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus RABGGTA MGD MGI:1860443
Rattus norvegicus RABGGTA RGD RGD:621697
Macaca mulatta RABGGTA VGNC VGNC:76640
Canis familiaris RABGGTA VGNC VGNC:45303
Felis catus RABGGTA VGNC VGNC:69207
Bos taurus RABGGTA VGNC VGNC:33670