Nr1h2 - nuclear receptor subfamily 1, group H, member 2 Gene
Also Known as LXRB; OR-1; LXRbeta; LXR beta
Species: Rattus norvegicus
Summary
Enables DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and retinoid X receptor binding activity. Contributes to sequence-specific DNA binding activity. Involved in regulation of gene expression; response to nutrient levels; and retinoic acid receptor signaling pathway. Predicted to be located in cytoplasm and nucleus. Biomarker of obesity. Human ortholog(s) of this gene implicated in obesity and type 2 diabetes mellitus. Orthologous to human NR1H2 (nuclear receptor subfamily 1 group H member 2). [provided by Alliance of Genome Resources, Apr 2022]
Nr1h2 Products (4)
| mRNA | Protein | Name |
|---|---|---|
| NM_001398609.1 | NP_001385538.1 | oxysterols receptor LXR-beta isoform a |
| NM_001398610.1 | NP_001385539.1 | oxysterols receptor LXR-beta isoform a |
| NM_001398611.1 | NP_001385540.1 | oxysterols receptor LXR-beta isoform b |
| NM_031626.3 | NP_113814.2 | oxysterols receptor LXR-beta isoform b |
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
oxysterols receptor LXR-beta |
|
|
Related Agents
- Pre-clinical Phase
Pre-clinical Phase
| Cat. No. | Product Name |
Effect
|
Purity |
Rare Diseases
|
|---|---|---|---|---|
| HY-RS09529 | NR1H2 Human Pre-designed siRNA Set A | / | Unkown | |
| HY-RS19726 | Nr1h2 Mouse Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS26222 | Nr1h2 Rat Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
Compound Screening Libraries
Virtual Screening
Customize Your Library
Drug Screening Service