Pygl - glycogen phosphorylase L Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 64035

Summary

Enables carbohydrate binding activity; glycogen Phosphorylase activity; and identical protein binding activity. Involved in 5-phosphoribose 1-diphosphate biosynthetic process and glycogen catabolic process. Located in cytoplasm. Used to study glycogen storage disease VI and lactic acidosis. Human ortholog(s) of this gene implicated in glycogen storage disease; glycogen storage disease VI; and lactic acidosis. Orthologous to human PYGL (glycogen Phosphorylase L). [provided by Alliance of Genome Resources, Apr 2022]

Pygl Products (1)

mRNA Protein Name
NM_022268.1 NP_071604.1 glycogen phosphorylase, liver form

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables carbohydrate binding IDA
IDA: Inferred from direct assay
6449198 RGD
enables glycogen phosphorylase activity IDA
IDA: Inferred from direct assay
114169 RGD
enables glycogen phosphorylase activity IMP
IMP: Inferred from mutant phenotype
15571236 RGD
enables identical protein binding IPI
IPI: Inferred from physical interaction
1554349 RGD
Biological Process GO Annotation Evidence References Source
involved in 5-phosphoribose 1-diphosphate biosynthetic process IMP
IMP: Inferred from mutant phenotype
15571236 RGD
involved in glycogen catabolic process IDA
IDA: Inferred from direct assay
114169 RGD
involved in glycogen metabolic process IDA
IDA: Inferred from direct assay
1554349 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

glycogen phosphorylase, liver form

  • liver glycogen phosphorylase

  • phosphorylase, glycogen, liver

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS11489 PYGL Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20806 Pygl Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27320 Pygl Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Pygl NCBI NCBI:5836