C19orf33 - chromosome 19 open reading frame 33 Gene

Also Known as IMUP; H2RSP; IMUP-1; IMUP-2

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 64073

About C19orf33

Cytogenetic location: 19q13.2 Genomic coordinates (GRCh38): 19:38,304,251-38,305,006 (from NCBI)

This gene has 4 transcripts (splice variants) and 46 orthologues. Biased expression in colon (RPKM 62.2), small intestine (RPKM 43.1) and 11 other tissues.

Summary

The protein encoded by this gene has been shown to be upregulated in SV40-immortalized fibroblasts as well as in endometrial carcinoma cells. The encoded protein is found primarily in the nucleus. This protein may play a role in placental development and diseases such as pre-eclampsia. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2015]

C19orf33 Products (2)

mRNA Protein Name
NM_001317801.2 NP_001304730.1 immortalization up-regulated protein isoform IMUP-2
NM_033520.3 NP_277055.1 immortalization up-regulated protein isoform IMUP-1

Gene Ontology

  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
NOT enables double-stranded DNA binding IDA
IDA: Inferred from direct assay
11080599 GOA
NOT enables single-stranded DNA binding IDA
IDA: Inferred from direct assay
11080599 GOA
Cellular Component GO Annotation Evidence References Source
located in nucleus IDA
IDA: Inferred from direct assay
11080599 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

immortalization up-regulated protein

  • HAI-2 related small protein

Related Diseases

Diseases Alias
Eclampsia

  • Eclampsia In Puerperium

  • Postpartum Eclampsia

  • Eclampsia, Postpartum

  • Puerperal Eclampsia
Pre-Eclampsia

  • Preeclampsia

  • Gestational Hypertension

  • Hypertension Induced By Pregnancy

  • Pre-Eclamptic Toxaemia

  • Pregnancy Associated Hypertension

  • Proteinuric Hypertension Of Pregnancy

  • Hypertension, Pregnancy-Induced, Susceptibility To

  • Preeclampsia/Eclampsia

  • Pregnancy Toxemia

  • Toxaemia Of Pregnancy

  • Gestational Proteinuric Hypertension

  • Pregnancy-Induced Hypertension

  • Toxemia Of Pregnancy

  • Preeclampsia, Susceptibility To

  • Transient Hypertension Of Pregnancy

  • Gestational [Pregnancy-Induced] Hypertension Without Significant Proteinuria

  • Gestational Hypertension Nos

  • Mild Proteinuric Hypertension Of Pregnancy

  • Pih - [Pregnancy-Induced Hypertension]

  • Pregnancy-Induced Hypertension Nos

  • Gestational [Pregnancy-Induced] Hypertension With Significant Proteinuria

  • Pe - [Pre-Eclampsia]

  • Pre-Eclampsia Nos

  • Pre-Eclamptic Nos

  • Pregnancy Pre-Eclampsia

  • Puerperal Pre-Eclampsia

  • Pre-Eclampsia Toxaemia

  • Toxaemia In Pregnancy

  • Pet - [Pre-Eclamptic Toxaemia]

  • Maternal Toxaemia
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS01704 C19orf33 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus C19orf33 RGD RGD:2319167
Mus musculus C19orf33 MGD MGI:1919525
Others C19orf33 NCBI