CLSTN2 - calsyntenin 2 Gene

Also Known as CS2; CSTN2; CDHR13; ALC-GAMMA; alcagamma

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 64084

About CLSTN2

Cytogenetic location: 3q23 Genomic coordinates (GRCh38): 3:139,935,185-140,577,397 (from NCBI)

This gene has 2 transcripts (splice variants), 280 orthologues and 2 paralogues. Biased expression in ovary (RPKM 37.4), brain (RPKM 15.7) and 6 other tissues.

Summary

Predicted to enable calcium ion binding activity. Predicted to be involved in positive regulation of synapse assembly and positive regulation of synaptic transmission. Predicted to be located in postsynaptic density. Predicted to be active in cell surface; glutamatergic synapse; and postsynaptic membrane. Predicted to be integral component of postsynaptic density membrane. [provided by Alliance of Genome Resources, Apr 2022]

CLSTN2 Products (1)

mRNA Protein Name
NM_022131.3 NP_071414.2 calsyntenin-2 precursor

CLSTN2 Protein Structure

Cadherin

Cadherin: Cadherin domain (166 - 253)

Laminin_G_3

Laminin_G_3: Concanavalin A-like lectin/glucanases superfamily (358 - 524)

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  • 800
  • 955 a.a.
Protein Preferred Names Protein Names

calsyntenin-2

  • alcadein gamma

Related Diseases

Diseases Alias
Astigmatism
Tetraamelia Syndrome

  • Tetra-Amelia Syndrome

  • Tetraamelia-Multiple Malformations Syndrome

  • Tetra-Amelia

  • Tetra-Amelia, Autosomal Recessive

  • Tetraamelia, Autosomal Recessive

  • Total Amelia

  • Zimmer Phocomelia

  • Tetams

  • Zimmer Taub Sova Syndrome
Bone Sarcoma
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS02841 CLSTN2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21107 Clstn2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27626 Clstn2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta CLSTN2 VGNC VGNC:71197
Canis familiaris CLSTN2 VGNC VGNC:39363
Felis catus CLSTN2 VGNC VGNC:60980
Mus musculus CLSTN2 MGD MGI:1929897
Rattus norvegicus CLSTN2 RGD RGD:621151
Bos taurus CLSTN2 VGNC VGNC:27467
Others CLSTN2 NCBI