Polr1e - polymerase (RNA) I polypeptide E Gene

Also Known as 53kDa; Paf53; Praf1; D030019D19Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 64424

Summary

Enables RNA polymerase I general transcription initiation factor binding activity. Acts upstream of or within RNA polymerase I preinitiation complex assembly. Located in nucleolus. Part of RNA polymerase I complex. Is expressed in several structures, including alimentary system; cardiovascular system; genitourinary system; nervous system; and sensory organ. Orthologous to human POLR1E (RNA polymerase I subunit E). [provided by Alliance of Genome Resources, Apr 2022]

Polr1e Products (4)

mRNA Protein Name
NM_001285800.1 NP_001272729.1 DNA-directed RNA polymerase I subunit RPA49 isoform a
NM_022811.3 NP_073722.1 DNA-directed RNA polymerase I subunit RPA49 isoform b
NM_001285800.1 NP_001272729.1 DNA-directed RNA polymerase I subunit RPA49 isoform a
NM_022811.3 NP_073722.1 DNA-directed RNA polymerase I subunit RPA49 isoform b

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables RNA polymerase I general transcription initiation factor binding IDA
IDA: Inferred from direct assay
8641287 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
8921381 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within RNA polymerase I preinitiation complex assembly IDA
IDA: Inferred from direct assay
8641287 MGI
Cellular Component GO Annotation Evidence References Source
part of RNA polymerase I complex IDA
IDA: Inferred from direct assay
8641287 MGI
located in nucleolus IDA
IDA: Inferred from direct assay
8641287 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

DNA-directed RNA polymerase I subunit RPA49

  • DNA-directed RNA polymerase I subunit E

  • RNA polymerase I associated factor (Paf53)

  • RNA polymerase I subunit A49

  • RNA polymerase I-associated factor 53

  • polymerase (RNA) I associated factor 1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS10841 POLR1E Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21911 Polr1e Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28428 Polr1e Rat Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Polr1e NCBI NCBI:64425