Ddb1 - damage-specific DNA binding protein 1 Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 64470

Summary

Enables damaged DNA binding activity. Predicted to be involved in several processes, including cellular protein metabolic process; positive regulation by virus of viral protein levels in host cell; and positive regulation of gluconeogenesis. Predicted to act upstream of or within Wnt signaling pathway; negative regulation of apoptotic process; and proteasomal protein catabolic process. Predicted to be located in cytoplasm and nucleoplasm. Predicted to be part of Cul4A-RING E3 ubiquitin Ligase complex and Cul4B-RING E3 ubiquitin Ligase complex. Predicted to be active in nucleus and site of double-strand break. Orthologous to human DDB1 (damage specific DNA binding protein 1). [provided by Alliance of Genome Resources, Apr 2022]

Ddb1 Products (1)

mRNA Protein Name
NM_171995.2 NP_741992.2 DNA damage-binding protein 1

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables damaged DNA binding IMP
IMP: Inferred from mutant phenotype
12145536 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

DNA damage-binding protein 1

  • damage-specific DNA binding protein 1, 127kDa

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-175890 DDB1 ligand-2 / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ddb1 NCBI NCBI:1642