MBL2 - Mbl2 mannose binding lectin 2 Gene

Also Known as Ab2-001; Ab2-011

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 64668

Summary

Enables several functions, including identical protein binding activity; monosaccharide binding activity; and phosphatidylinositol-4-phosphate binding activity. Involved in positive regulation of complement activation and positive regulation of protein processing. Located in extracellular space. Part of protein-containing complex. Human ortholog(s) of this gene implicated in several diseases, including autoimmune disease (multiple); Bacterial infectious disease (multiple); Fungal infectious disease (multiple); liver disease (multiple); and lung disease (multiple). Orthologous to human MBL2 (mannose binding lectin 2). [provided by Alliance of Genome Resources, Apr 2022]

MBL2 Products (1)

mRNA Protein Name
NM_022704.2 NP_073195.2 mannose-binding protein C precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables D-mannose binding IDA
IDA: Inferred from direct assay
10589993 RGD
enables calcium ion binding IDA
IDA: Inferred from direct assay
9922166 RGD
enables galactose binding IDA
IDA: Inferred from direct assay
8557671 RGD
enables identical protein binding IDA
IDA: Inferred from direct assay
8557671 RGD
enables identical protein binding IPI
IPI: Inferred from physical interaction
9230118 RGD
enables phosphatidylinositol-4-phosphate binding IDA
IDA: Inferred from direct assay
9315725 RGD
enables protease binding IPI
IPI: Inferred from physical interaction
11337510 RGD
Biological Process GO Annotation Evidence References Source
involved in positive regulation of complement activation IDA
IDA: Inferred from direct assay
9920905 RGD
involved in positive regulation of protein processing IDA
IDA: Inferred from direct assay
20118239 RGD
Cellular Component GO Annotation Evidence References Source
located in extracellular space IDA
IDA: Inferred from direct assay
3124748 RGD
part of protein-containing complex IMP
IMP: Inferred from mutant phenotype
9920905 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

mannose-binding protein C

  • MBP-C

  • RA-reactive factor P28A subunit

  • RARF/P28A

  • mannan-binding protein

  • mannose binding lectin 2 (protein C)

  • mannose-binding lectin (protein C) 2

  • mannose-binding protein C (liver)

  • mannose-binding protein C-like

  • ra-reactive factor polysaccharide-bin

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS08188 MBL2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18484 Mbl2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24966 Mbl2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens MBL2 NCBI NCBI:4153