IPPK - inositol-pentakisphosphate 2-kinase Gene

Homo sapiens

Also known as IP5K; IPK1; C9orf12; INSP5K2; bA476B13.1

Gene ID: 64768 | Gene type: protein coding

About IPPK

Cytogenetic location: 9q22.31 Genomic coordinates (GRCh38): 9:92,613,183-92,670,131 (from NCBI)

This gene has 3 transcripts (splice variants) and 205 orthologues. Ubiquitous expression in skin (RPKM 15.1), esophagus (RPKM 8.3) and 24 other tissues.

Summary

The protein encoded by this gene is a kinase that phosphorylates position 2 of inositol-1,3,4,5,6-pentakisphosphate to form inositol-1,2,3,4,5,6-hexakisphosphate (InsP6). InsP6 has a variety of functions, including stimulation of DNA repair, endocytosis, and mRNA export. [provided by RefSeq, Nov 2010]

IPPK Products(1)

mRNA	Protein	Name
NM_022755.6	NP_073592.1	inositol-pentakisphosphate 2-kinase

IPPK Protein Structure

Ins_P5_2-kin

0
100
200
300
400
491 a.a.

Protein Preferred Names

Protein Names

inositol-pentakisphosphate 2-kinase

IPK1 homolog

Related Diseases

Diseases

Alias

Lethal Congenital Contracture Syndrome 1

LCCS1	Multiple Contracture Syndrome, Finnish Type
Lccs	Lethal Autosomal Recessive Syndrome Of Multiple Congenital Contractures
Lethal Congenital Contracture Syndrome Type 1	Herva Disease
Multiple Contracture Syndrome Finnish Type	Contracture Syndrome, Lethal, Congenital, Type 1

Spastic Paraplegia 63, Autosomal Recessive

SPG63	Hereditary Spastic Paraplegia 63
Spastic Paraplegia 63	Autosomal Recessive Spastic Paraplegia 63
Autosomal Recessive Spastic Paraplegia Type 63	Paraplegia, Spastic, Type 63, Autosomal Recessive

Lethal Congenital Contracture Syndrome

Lccs	Lethal Congenital Contracture Syndrome 1

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS06874	IPPK Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Macaca mulatta	IPPK	VGNC	VGNC:73597
Mus musculus	IPPK	MGD	MGI:1922928
Rattus norvegicus	IPPK	RGD	RGD:1311271
Bos taurus	IPPK	VGNC	VGNC:56974
Canis familiaris	IPPK	VGNC	VGNC:42071