country

Change Language

EN - English
FR - Français
DE - Deutsch
ES - Español
JA - 日本語
KO - 한국어

Country or Region:

United States

Product Name	Size / Unit Price	Qty

Total: USD 0.00 Checkout

CASD1 - CAS1 domain containing 1 Gene

Also Known as SOAT; C7orf12; NBLA04196

Species: Homo sapiens

Gene Type: protein coding

Gene ID: 64921

About CASD1

Cytogenetic location: 7q21.3 Genomic coordinates (GRCh38): 7:94,509,809-94,634,172 (from NCBI)

This gene has 6 transcripts (splice variants) and 208 orthologues. Ubiquitous expression in adrenal (RPKM 10.9), brain (RPKM 10.1) and 25 other tissues.

Summary

Enables N-acetylneuraminate 7-O(or 9-O)-acetyltransferase activity. Involved in carbohydrate metabolic process. Is integral component of Golgi membrane. [provided by Alliance of Genome Resources, Apr 2022]

CASD1 Products (4)

mRNA	Protein	Name
NM_001363426.1	NP_001350355.1	N-acetylneuraminate 9-O-acetyltransferase isoform 2
NM_001363427.1	NP_001350356.1	N-acetylneuraminate 9-O-acetyltransferase isoform 3
NM_001363428.1	NP_001350357.1	N-acetylneuraminate 9-O-acetyltransferase isoform 4
NM_022900.5	NP_075051.4	N-acetylneuraminate 9-O-acetyltransferase isoform 1

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	References	Source
enables N-acetylneuraminate 7-O(or 9-O)-acetyltransferase activity	IDA IDA: Inferred from direct assay	26169044	GOA

Biological Process GO Annotation	Evidence	References	Source
involved in carbohydrate metabolic process	IDA IDA: Inferred from direct assay	26169044	GOA

Cellular Component GO Annotation	Evidence	References	Source
located in Golgi membrane	IDA IDA: Inferred from direct assay	26169044	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

CASD1 Protein Structure

PC-Esterase

Cas1_AcylT

0
200
400
600
797 a.a.

Protein Preferred Names	Protein Names
N-acetylneuraminate 9-O-acetyltransferase	CAS1 domain-containing protein 1

Related Diseases

Diseases	Alias
Sgce Myoclonus-Dystonia	Dystonia 11 Dyt11 Dyt-Sgce
Dystonia 11, Myoclonic	Myoclonic Dystonia Myoclonus-Dystonia Syndrome DYT11 Myoclonic Dystonia 11 Alcohol-Responsive Dystonia Myoclonus, Hereditary Essential Dystonia-11, Myoclonic Myoclonus-Dystonia Dystonia 11 Hereditary Essential Myoclonus Dystonia, Alcohol-Responsive Dyt-Sgce Dystonia, Alcohol Responsive Dystonia-11 Dystonia, Myoclonic Dystonia, Myoclonic, Type 11
Citrullinemia, Type Ii, Neonatal-Onset	NICCD Citrin Deficiency Neonatal Intrahepatic Cholestasis Due To Citrin Deficiency Citrullinemia, Type Ii, Neonatal-Onset, With Or Without Failure To Thrive And Dyslipidemia Cholestasis, Neonatal Intrahepatic, Caused By Citrin Deficiency Neonatal-Onset Type Ii Citrullinemia Neonatal Intrahepatic Cholestasis Caused By Citrin Deficiency Neonatal-Onset Citrullinemia Type 2 Neonatal-Onset Citrullinemia Type Ii Neonatal-Onset Type 2 Citrullinemia Adult-Onset Citrullinemia Type 2
Atrial Septal Defect 2	ASD2 Atrial Heart Septal Defect 2 Atrial Septal Defect-2 Asd Ii Septal Defect, Atrial, Type 2

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS01937	CASD1 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Felis catus	CASD1	VGNC	VGNC:60377
Mus musculus	CASD1	MGD	MGI:2384865
Bos taurus	CASD1	VGNC	VGNC:26775
Canis familiaris	CASD1	VGNC	VGNC:38728
Rattus norvegicus	CASD1	RGD	RGD:1596912
Macaca mulatta	CASD1	VGNC	VGNC:70563
Others	CASD1	NCBI