Sostdc1 - sclerostin domain containing 1 Gene

Also Known as Wise; Sostl; USAG-1; ectodin; 0610006G05Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 66042

Summary

Predicted to enable BMP binding activity and BMP Receptor activity. Acts upstream of or within several processes, including animal organ development; negative regulation of cell fate commitment; and negative regulation of signal transduction. Located in extracellular space. Is expressed in several structures, including alimentary system; genitourinary system; limb; nervous system; and sensory organ. Orthologous to human SOSTDC1 (sclerostin domain containing 1). [provided by Alliance of Genome Resources, Apr 2022]

Sostdc1 Products (1)

mRNA Protein Name
NM_025312.3 NP_079588.1 sclerostin domain-containing protein 1 precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
14623234 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of BMP signaling pathway IDA
IDA: Inferred from direct assay
16179481 MGI
acts upstream of BMP signaling pathway IGI
IGI: Inferred from genetic interaction
16179481 MGI
acts upstream of canonical Wnt signaling pathway IMP
IMP: Inferred from mutant phenotype
22509524 MGI
acts upstream of cell fate commitment IMP
IMP: Inferred from mutant phenotype
22509524 MGI
acts upstream of epithelial cell fate commitment IMP
IMP: Inferred from mutant phenotype
22509524 MGI
acts upstream of or within hair follicle morphogenesis IMP
IMP: Inferred from mutant phenotype
22509524 MGI
acts upstream of or within mammary gland bud morphogenesis IMP
IMP: Inferred from mutant phenotype
22509524 MGI
acts upstream of or within negative regulation of BMP signaling pathway IDA
IDA: Inferred from direct assay
14623234 MGI
acts upstream of or within negative regulation of BMP signaling pathway IGI
IGI: Inferred from genetic interaction
16179481 MGI
acts upstream of or within negative regulation of canonical Wnt signaling pathway IMP
IMP: Inferred from mutant phenotype
22509524 MGI
acts upstream of or within negative regulation of cell fate commitment IMP
IMP: Inferred from mutant phenotype
22509524 MGI
acts upstream of or within odontogenesis of dentin-containing tooth IGI
IGI: Inferred from genetic interaction
16179481 MGI
acts upstream of or within odontogenesis of dentin-containing tooth IMP
IMP: Inferred from mutant phenotype
16179481 MGI
acts upstream of or within pattern specification process IMP
IMP: Inferred from mutant phenotype
16179481 MGI
Cellular Component GO Annotation Evidence References Source
located in extracellular space IDA
IDA: Inferred from direct assay
14623234 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

sclerostin domain-containing protein 1

  • cystine-knot containing secreted protein

  • ectodermal BMP inhibitor

  • sclerostin-like protein

  • uterine sensitization-associated gene 1 protein

  • uterine sensitization-associated protein 1

Recombinant Sostdc1 Proteins

Cat. No. Product Name Accession Purity
HY-P79350 USAG-1 Protein, Mouse (HEK293, His) Q9CQN4 (F24-S206) ≥ 95%, as determined by reducing SDS-PAGE.

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS13579 SOSTDC1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22046 Sostdc1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28564 Sostdc1 Rat Pre-designed siRNA Set A / Unkown
Inhibitory Antibodies (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P992304 Anti-SOSTDC1 Antibody / Unkown
HY-P992311 Anti-USAG-1 Antibody / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Sostdc1 NCBI NCBI:25928