Pam16 - presequence translocase-asssociated motor 16 Gene

Also Known as Tim16; Magmas; Timm16; CGI-136; 2010110I09Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 66449

Summary

Acts upstream of or within DNA biosynthetic process and negative regulation of apoptotic signaling pathway. Located in mitochondrion. Part of PAM complex, Tim23 associated import motor. Is expressed in several structures, including alimentary system; central nervous system; egg cylinder; genitourinary system; and lung. Human ortholog(s) of this gene implicated in spondylometaphyseal dysplasia Megarbane-Dagher-Melike type. Orthologous to human PAM16 (presequence translocase associated motor 16). [provided by Alliance of Genome Resources, Apr 2022]

Pam16 Products (1)

mRNA Protein Name
NM_025571.1 NP_079847.1 mitochondrial import inner membrane translocase subunit TIM16

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
24856930 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within DNA biosynthetic process IMP
IMP: Inferred from mutant phenotype
20719856 MGI
acts upstream of or within negative regulation of apoptotic signaling pathway IMP
IMP: Inferred from mutant phenotype
20719856 MGI
Cellular Component GO Annotation Evidence References Source
part of PAM complex, Tim23 associated import motor IDA
IDA: Inferred from direct assay
24856930 MGI
located in cytoplasm IDA
IDA: Inferred from direct assay
12704206 MGI
located in mitochondrion IDA
IDA: Inferred from direct assay
20719856 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

mitochondrial import inner membrane translocase subunit TIM16

  • magmas processed gene 1

  • mitochondria associated granulocyte macrophage CSF signaling molecule

  • mitochondria-associated protein involved in granulocyte-macrophage colony-stimulating factor signal transduction

  • presequence translocase-asssociated motor 16

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS10012 PAM16 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19468 Pam16 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25961 Pam16 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Pam16 NCBI NCBI:51025