Rnf128 - ring finger protein 128 Gene

Also Known as GRAIL; Greul1; 1300002C13Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 66889

Summary

Enables ubiquitin protein Ligase activity. Acts upstream of or within negative regulation of cytokine production. Located in Golgi apparatus; endoplasmic reticulum; and late endosome. Is expressed in several structures, including alimentary system; extraembryonic component; genitourinary system; nervous system; and sensory organ. Orthologous to human RNF128 (ring finger protein 128). [provided by Alliance of Genome Resources, Apr 2022]

Rnf128 Products (2)

mRNA Protein Name
NM_001254761.1 NP_001241690.1 E3 ubiquitin-protein ligase RNF128 isoform 2 precursor
NM_023270.5 NP_075759.3 E3 ubiquitin-protein ligase RNF128 isoform 1 precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables ubiquitin protein ligase activity IDA
IDA: Inferred from direct assay
12435366 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within negative regulation of cytokine production IDA
IDA: Inferred from direct assay
12705856 MGI
Cellular Component GO Annotation Evidence References Source
located in Golgi apparatus IDA
IDA: Inferred from direct assay
12705856 MGI
located in endoplasmic reticulum IDA
IDA: Inferred from direct assay
12705856 MGI
located in late endosome IDA
IDA: Inferred from direct assay
12705856 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

E3 ubiquitin-protein ligase RNF128

  • RING-type E3 ubiquitin transferase RNF128

  • gene related to anergy in lymphocytes protein

  • goliath-related E3 ubiquitin-protein ligase 1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS12046 RNF128 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21919 Rnf128 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28435 Rnf128 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Rnf128 NCBI NCBI:79589