Nuf2 - NUF2, NDC80 kinetochore complex component Gene

Predicted to be involved in kinetochore organization; mitotic spindle organization; and nuclear division. Predicted to act upstream of or within attachment of spindle microtubules to kinetochore. Predicted to be located in cytosol; kinetochore; and nucleoplasm. Predicted to be part of Ndc80 complex. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; respiratory system; and sensory organ. Human ortholog(s) of this gene implicated in castration-resistant prostate carcinoma and pancreatic Cancer. Orthologous to human NUF2 (NUF2 component of NDC80 kinetochore complex). [provided by Alliance of Genome Resources, Apr 2022]