Trim62 - tripartite motif-containing 62 Gene

Also Known as Dear1; 6330414G21Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 67525

Summary

Predicted to enable identical protein binding activity; transcription coactivator activity; and ubiquitin protein Ligase activity. Involved in positive regulation of Antifungal innate immune response. Acts upstream of or within negative regulation of epithelial to mesenchymal transition. Predicted to be active in cytoplasm. Is expressed in several structures, including central nervous system; genitourinary system; maxillary process; sensory organ; and submandibular gland primordium. Orthologous to human TRIM62 (tripartite motif containing 62). [provided by Alliance of Genome Resources, Apr 2022]

Trim62 Products (3)

mRNA Protein Name
NM_001370756.1 NP_001357685.1 E3 ubiquitin-protein ligase TRIM62 isoform 1
NM_001370757.1 NP_001357686.1 E3 ubiquitin-protein ligase TRIM62 isoform 3
NM_178110.3 NP_835211.1 E3 ubiquitin-protein ligase TRIM62 isoform 2

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
acts upstream of or within negative regulation of epithelial to mesenchymal transition IMP
IMP: Inferred from mutant phenotype
24890125 MGI
involved in positive regulation of antifungal innate immune response IMP
IMP: Inferred from mutant phenotype
26488816 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

E3 ubiquitin-protein ligase TRIM62

  • RING-type E3 ubiquitin transferase TRIM62

  • tripartite motif-containing protein 62

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-115497 BRD5529 Inhibitor 98.94% Unkown
HY-RS15062 TRIM62 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19081 Trim62 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25572 Trim62 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Trim62 NCBI NCBI:55223