Itga2b - integrin subunit alpha 2b Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 685269

Summary

Enables fibrinogen binding activity. Involved in platelet aggregation and positive regulation of leukocyte migration. Located in cell surface. Human ortholog(s) of this gene implicated in Glanzmann's thrombasthenia; platelet-type bleeding disorder 16; thrombocytopenia; and von Willebrand's disease 1. Orthologous to human ITGA2B (Integrin subunit alpha 2b). [provided by Alliance of Genome Resources, Apr 2022]

Itga2b Products (1)

mRNA Protein Name
XM_001063315.7 XP_001063315.1 integrin alpha-IIb

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables fibrinogen binding IDA
IDA: Inferred from direct assay
11278919 RGD
Biological Process GO Annotation Evidence References Source
involved in positive regulation of leukocyte migration IMP
IMP: Inferred from mutant phenotype
11705748 RGD
Cellular Component GO Annotation Evidence References Source
located in cell surface IDA
IDA: Inferred from direct assay
11278919 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

integrin alpha-IIb

  • integrin alpha 2b (Cd41b)

  • integrin, alpha 2B

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS06949 ITGA2B Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19782 Itga2b Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26279 Itga2b Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Itga2b NCBI NCBI:3674