Trim8 - tripartite motif-containing 8 Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 688785

Summary

Predicted to enable protein homodimerization activity and transcription coactivator activity. Predicted to be involved in several processes, including defense response to Other organism; negative regulation of viral transcription; and positive regulation of NF-kappaB transcription factor activity. Predicted to act upstream of or within positive regulation of protein localization to nucleus and stem cell population maintenance. Predicted to be located in PML body and cytosol. Orthologous to human TRIM8 (tripartite motif containing 8). [provided by Alliance of Genome Resources, Apr 2022]

Trim8 Products (1)

mRNA Protein Name
NM_001128083.2 NP_001121555.1 E3 ubiquitin-protein ligase TRIM8

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables mitogen-activated protein kinase kinase kinase binding IPI
IPI: Inferred from physical interaction
27956576 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

E3 ubiquitin-protein ligase TRIM8

  • probable E3 ubiquitin-protein ligase TRIM8

  • tripartite motif protein 8

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS15072 TRIM8 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21796 Trim8 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28312 Trim8 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Trim8 NCBI NCBI:81603