Disp1 - dispatched RND transporter family member 1 Gene

Also Known as DispA; 1190008H24Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 68897

Summary

Enables peptide transmembrane transporter activity. Acts upstream of or within several processes, including determination of left/right symmetry; patched ligand maturation; and smoothened signaling pathway. Predicted to be located in membrane. Predicted to be integral component of membrane. Is expressed in several structures, including embryo ectoderm; embryo mesenchyme; foot bone; notochord; and palatal shelf. Orthologous to human DISP1 (dispatched RND transporter family member 1). [provided by Alliance of Genome Resources, Apr 2022]

Disp1 Products (4)

mRNA Protein Name
NM_001278218.1 NP_001265147.1 protein dispatched homolog 1
NM_001278219.1 NP_001265148.1 protein dispatched homolog 1
NM_001278220.1 NP_001265149.1 protein dispatched homolog 1
NM_026866.3 NP_081142.3 protein dispatched homolog 1
Molecular Function GO Annotation Evidence References Source
enables molecular carrier activity IDA
IDA: Inferred from direct assay
12372301 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within determination of left/right symmetry IMP
IMP: Inferred from mutant phenotype
12421714 MGI
acts upstream of or within dorsal/ventral pattern formation IMP
IMP: Inferred from mutant phenotype
15755804 MGI
acts upstream of or within embryonic pattern specification IMP
IMP: Inferred from mutant phenotype
12372301 MGI
acts upstream of or within patched ligand maturation IDA
IDA: Inferred from direct assay
12421714 MGI
acts upstream of or within patched ligand maturation IMP
IMP: Inferred from mutant phenotype
12421714 MGI
acts upstream of or within peptide transport IDA
IDA: Inferred from direct assay
12372301 MGI
acts upstream of or within peptide transport IMP
IMP: Inferred from mutant phenotype
12421714 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

protein dispatched homolog 1

  • dispatched A

  • dispatched homolog 1

  • mdispa

  • twelve-pass transmembrane protein

Orthologs Information

Species Symbol Source ID
Homo sapiens Disp1 NCBI NCBI:84976