Mapk11 - mitogen-activated protein kinase 11 Gene

Also Known as p38beta

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 689314

About Mapk11

Primary_assembly 7: 120,218,478-120,225,395 reverse strand.mRatBN7.2:CM026980.1

This gene has 3 transcripts (splice variants), 201 orthologues, 21 paralogues and is associated with 5 phenotypes. Biased expression in Brain (RPKM 67.3), Lung (RPKM 23.) and 7 other tissues.

Summary

Enables ATP binding activity and MAP kinase activity. Involved in protein phosphorylation. Predicted to be active in cytosol and nucleus. Orthologous to human MAPK11 (mitogen-activated protein kinase 11). [provided by Alliance of Genome Resources, Apr 2022]

Mapk11 Products (1)

mRNA Protein Name
NM_001109532.2 NP_001103002.2 mitogen-activated protein kinase 11

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables ATP binding IDA
IDA: Inferred from direct assay
16879317 RGD
enables MAP kinase activity IDA
IDA: Inferred from direct assay
16879317 RGD
Biological Process GO Annotation Evidence References Source
involved in protein phosphorylation IDA
IDA: Inferred from direct assay
16879317 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Mapk11 Protein Structure

PKc_like

PKc_like: cl21453 (7 - 356)

  • 0
  • 100
  • 200
  • 300
  • 371 a.a.
Protein Preferred Names Protein Names

mitogen-activated protein kinase 11

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-186241 NuP-3 Inhibitor / Unkown
HY-RS08098 MAPK11 Human Pre-designed siRNA Set A / Unkown
HY-RS08099 Mapk11 Mouse Pre-designed siRNA Set A / Unkown
HY-RS08100 Mapk11 Rat Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Mapk11 NCBI NCBI:5600