Gmppa - GDP-mannose pyrophosphorylase A Gene

Also Known as 1810012N01Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 69080

Summary

Predicted to enable nucleotidyltransferase activity. Predicted to be involved in biosynthetic process. Predicted to be active in cytoplasm. Is expressed in several structures, including adrenal gland; alimentary system; central nervous system; eye; and gonad. Human ortholog(s) of this gene implicated in alacrima, achalasia, and impaired intellectual development syndrome. Orthologous to human GMPPA (GDP-mannose pyrophosphorylase A). [provided by Alliance of Genome Resources, Apr 2022]

Gmppa Products (4)

mRNA Protein Name
NM_001357169.1 NP_001344098.1 mannose-1-phosphate guanyltransferase alpha isoform 1
NM_001357170.1 NP_001344099.1 mannose-1-phosphate guanyltransferase alpha isoform 1
NM_001357171.1 NP_001344100.1 mannose-1-phosphate guanyltransferase alpha isoform 2
NM_133708.4 NP_598469.1 mannose-1-phosphate guanyltransferase alpha isoform 1

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
acts upstream of or within GDP-mannose biosynthetic process IMP
IMP: Inferred from mutant phenotype
33755596 MGI
acts upstream of or within GDP-mannose metabolic process IMP
IMP: Inferred from mutant phenotype
33755596 MGI
acts upstream of or within cognition IMP
IMP: Inferred from mutant phenotype
33755596 MGI
acts upstream of or within glycoprotein metabolic process IMP
IMP: Inferred from mutant phenotype
33755596 MGI
acts upstream of or within motor behavior IMP
IMP: Inferred from mutant phenotype
33755596 MGI
acts upstream of or within muscle organ morphogenesis IMP
IMP: Inferred from mutant phenotype
33755596 MGI
involved in negative regulation of biosynthetic process IMP
IMP: Inferred from mutant phenotype
33755596 MGI
involved in negative regulation of nucleobase-containing compound metabolic process IMP
IMP: Inferred from mutant phenotype
33755596 MGI
involved in negative regulation of phosphate metabolic process IMP
IMP: Inferred from mutant phenotype
33755596 MGI
involved in negative regulation of small molecule metabolic process IMP
IMP: Inferred from mutant phenotype
33755596 MGI
acts upstream of or within neuromuscular process IMP
IMP: Inferred from mutant phenotype
33755596 MGI
acts upstream of or within neuron apoptotic process IMP
IMP: Inferred from mutant phenotype
33755596 MGI
acts upstream of or within protein glycosylation IMP
IMP: Inferred from mutant phenotype
33755596 MGI
acts upstream of or within skeletal muscle organ development IMP
IMP: Inferred from mutant phenotype
33755596 MGI
acts upstream of or within telencephalon development IMP
IMP: Inferred from mutant phenotype
33755596 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

mannose-1-phosphate guanyltransferase alpha

  • GTP-mannose-1-phosphate guanylyltransferase alpha

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS05524 GMPPA Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20937 Gmppa Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27454 Gmppa Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Gmppa NCBI NCBI:29926