Gins1 - GINS complex subunit 1 (Psf1 homolog) Gene

Also Known as PSF1; Gins4; mKIAA0186; 2810418N01Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 69270

Summary

Acts upstream of or within DNA replication and inner cell mass cell proliferation. Located in cytoplasm and nucleus. Is expressed in several structures, including alimentary system; brain; genitourinary system; respiratory system; and sensory organ. Human ortholog(s) of this gene implicated in immunodeficiency 55. Orthologous to human GINS1 (GINS complex subunit 1). [provided by Alliance of Genome Resources, Apr 2022]

Gins1 Products (2)

mRNA Protein Name
NM_001163476.1 NP_001156948.1 DNA replication complex GINS protein PSF1 isoform 2
NM_027014.1 NP_081290.1 DNA replication complex GINS protein PSF1 isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
16338220 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within DNA replication IMP
IMP: Inferred from mutant phenotype
16287864 MGI
acts upstream of or within inner cell mass cell proliferation IMP
IMP: Inferred from mutant phenotype
16287864 MGI
Cellular Component GO Annotation Evidence References Source
located in cytoplasm IDA
IDA: Inferred from direct assay
16338220 MGI
located in nucleus IDA
IDA: Inferred from direct assay
16338220 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

DNA replication complex GINS protein PSF1

  • GINS complex subunit 4 (Sld5 homolog)

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (5)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-W279260 APOBEC3G-IN-1 Inhibitor 96.88% Unkown
HY-RS05429 GIN1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS05430 GINS1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20936 Gins1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27453 Gins1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Gins1 NCBI NCBI:9837