Lman1 - lectin, mannose-binding, 1 Gene

Also Known as P58; MR60; gp58; F5F8D; MCFD1; ERGIC53; C730041J05; 2610020P13Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 70361

Summary

Predicted to enable identical protein binding activity and mannose binding activity. Acts upstream of or within endoplasmic reticulum organization. Located in several cellular components, including COPII-coated ER to Golgi transport vesicle; endoplasmic reticulum-Golgi intermediate compartment; and sarcomere. Is expressed in pancreas epithelium. Human ortholog(s) of this gene implicated in factor V deficiency and factor XIII deficiency. Orthologous to human LMAN1 (lectin, mannose binding 1). [provided by Alliance of Genome Resources, Apr 2022]

Lman1 Products (2)

mRNA Protein Name
NM_001172062.1 NP_001165533.1 protein ERGIC-53 precursor
NM_027400.3 NP_081676.1 protein ERGIC-53 precursor

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
acts upstream of or within endoplasmic reticulum organization IMP
IMP: Inferred from mutant phenotype
21795745 MGI
Cellular Component GO Annotation Evidence References Source
located in COPII-coated ER to Golgi transport vesicle IDA
IDA: Inferred from direct assay
19966784 MGI
located in Golgi apparatus IDA
IDA: Inferred from direct assay
10787428 MGI
located in endoplasmic reticulum-Golgi intermediate compartment IDA
IDA: Inferred from direct assay
14645249 MGI
located in sarcomere IDA
IDA: Inferred from direct assay
14728599 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

protein ERGIC-53

  • ER-Golgi intermediate compartment 53 kDa protein

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS07703 LMAN1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22612 Lman1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS29127 Lman1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Lman1 NCBI NCBI:3998