ATR - ATR serine/threonine kinase Gene

Species: Macaca mulatta

Gene Type: protein coding
Gene ID: 714443

About ATR

Primary_assembly 2: 44,574,979-44,696,002 reverse strand.Mmul_10:CM014337.1

This gene has 3 transcripts (splice variants), 209 orthologues and 5 paralogues.

ATR Products (4)

mRNA Protein Name
XM_015131991.2 XP_014987477.2 serine/threonine-protein kinase ATR isoform X1
XM_028843749.1 XP_028699582.1 serine/threonine-protein kinase ATR isoform X4
XM_015131993.2 XP_014987479.2 serine/threonine-protein kinase ATR isoform X3
XM_015131992.2 XP_014987478.2 serine/threonine-protein kinase ATR isoform X2

ATR Protein Structure

UME

UME: smart00802 (1118 - 1223)

FAT

FAT: pfam02259 (1770 - 2091)

TEL1

TEL1: cl34875 (2132 - 2643)

PIKKc_ATR

PIKKc_ATR: cd00892 (2292 - 2566)

  • 0
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  • 2000
  • 2500
  • 2644 a.a.
Protein Preferred Names Protein Names

serine/threonine-protein kinase ATR

  • ataxia telangiectasia and Rad3 related

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Bioactive Molecules (5)
Cat. No. Product Name Effect
Purity Phase
HY-19323 Ceralasertib Inhibitor 99.76% Phase 3
HY-13902 Berzosertib Inhibitor 99.67% Phase 2
HY-101566 Elimusertib Inhibitor 99.91% Phase 2
HY-139609 Camonsertib Inhibitor 99.99% Phase 2
HY-101566A Elimusertib hydrochloride Inhibitor 99.85% Phase 2

Pre-clinical Phase

Bioactive Molecules (31)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-14731 VE-821 Inhibitor 99.67% Unkown
HY-136270 Gartisertib Inhibitor 99.77% Unkown
HY-15557 AZ20 Inhibitor 99.40% Unkown
HY-15520 CGK733 Inhibitor 99.71% Unkown
HY-15521 ETP-46464 Inhibitor 99.54% Unkown
HY-N6954 Garcinone C Activator 99.51% Unkown
HY-159480 AD1058 Inhibitor 98.11% Unkown
HY-P10280 ATR kinase substrate peptide Substrate 99.30% Unkown
HY-161615 PROTAC ATR degrader-2 Degrader 99.73% Unkown
HY-13816 NU6027 Inhibitor 98.01% Unkown
HY-157767 Abd110 Inhibitor 98.67% Unkown
HY-147569 ATR-IN-17 Inhibitor / Unkown
HY-147567 ATR-IN-15 Inhibitor / Unkown
HY-147566 ATR-IN-14 Inhibitor / Unkown
HY-182017 ATR ligand 2 Ligand / Unkown
HY-13902A Berzosertib hydrochloride Inhibitor 98.77% Unkown
HY-161838 ICT10336 Inhibitor / Unkown
HY-182016 PROTAC ATR degrader-3 Degrader / Unkown
HY-151915 ATR-IN-20 Inhibitor / Unkown
HY-174828 ATR/PARP1-IN-1 Inhibitor / Unkown
HY-147568 ATR-IN-16 Inhibitor / Unkown
HY-153393 ATR-IN-21 Inhibitor / Unkown
HY-147190 ATR-IN-19 Inhibitor / Unkown
HY-144214 ATR-IN-10 Inhibitor / Unkown
HY-147570 ATR-IN-18 Inhibitor / Unkown
HY-147565 ATR-IN-13 Inhibitor / Unkown
HY-172247 ATR-IN-31 Inhibitor / Unkown
HY-153729 ATR-IN-29 Inhibitor / Unkown
HY-161616 ATR-IN-30 / Unkown
HY-141478 Antitumor agent-28 Inhibitor / Unkown
HY-N18301 Americanin A Activator / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens ATR NCBI NCBI:545