ATR-IN-10
ATR-IN-10 is a potent and highly selective inhibitor of ataxia telangiectasia mutated and Rad3-Related (ATR) kinase with an IC50 value of 2.978 μM.
For research use only. We do not sell to patients.
- CAS No.: 2713577-93-4
- Formula: C27H24N4O
- Molecular Weight:420.51
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Description
IC50 & Target
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ATR 2.978 μM (IC50) |
Chemical Information
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CAS No. 2713577-93-4
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Molecular Weight 420.51
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Formula C27H24N4O
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SMILES
C[C@H]1N(C2=C3C=C(C4=CC=CC=C4)C=CC3=NC(C5=CC=CC6=C5C=CN6)=N2)CCOC1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)