ATR-IN-15
ATR-IN-15 (compound 1) is an orally active and potent ATR kinase inhibitor, with an IC50 of 8 nM. ATR-IN-15 also inhibits human colon tumor cells LoVo, DNA-PK and PI3K, with IC50 values of 47, 663 and 5131 nM, respectively.
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- CAS No.: 2756665-52-6
- Formule: C19H22N8O
- Masse moléculaire:378.43
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
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ATR 8 nM (IC50) |
PI3K 5131 nM (IC50) |
ATM > 10000 nM (IC50) |
Chemical Information
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CAS No. 2756665-52-6
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Masse moléculaire 378.43
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Formule C19H22N8O
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SMILES
CC1=NC(C2=CC=NN2)=C3N=C(C=C(N13)N4[C@H](C)COCC4)C5=CC=NN5C
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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