ATR-IN-15
ATR-IN-15 (compound 1) is an orally active and potent ATR kinase inhibitor, with an IC50 of 8 nM. ATR-IN-15 also inhibits human colon tumor cells LoVo, DNA-PK and PI3K, with IC50 values of 47, 663 and 5131 nM, respectively.
For research use only. We do not sell to patients.
- CAS No.: 2756665-52-6
- Formula: C19H22N8O
- Molecular Weight:378.43
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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ATR 8 nM (IC50) |
PI3K 5131 nM (IC50) |
ATM > 10000 nM (IC50) |
Chemical Information
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CAS No. 2756665-52-6
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Molecular Weight 378.43
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Formula C19H22N8O
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SMILES
CC1=NC(C2=CC=NN2)=C3N=C(C=C(N13)N4[C@H](C)COCC4)C5=CC=NN5C
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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