ATR-IN-14
ATR-IN-14 (compound 1) is a potent ATR kinase inhibitor. ATR-IN-14 inhibits ATR signaling pathways downstream CHKI protein phosphorylation, with inhibition of 98.03% at 25 nM. ATR-IN-14 shows good anticancer activity in LoVo cells, with an IC50 of 64 nM.
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- CAS No.: 2765785-88-2
- Formule: C20H20FN7O
- Masse moléculaire:393.42
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
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Activité biologique
Description
IC50 & Target
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ATR |
Chemical Information
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CAS No. 2765785-88-2
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Masse moléculaire 393.42
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Formule C20H20FN7O
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SMILES
C[C@@H]1COCCN1C2=NC3=C(N=CC(F)=C3C(C4=CC=NN4C)=C2)C5=CC=NN5
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
ATR-IN-14 Related Classifications
HY-147566 Related Classifications
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