Antitumor agent-28
Antitumor agent-28 selectively inhibits ataxia telangiectasia mutated (ATM) kinase. Antitumor agent-28 prevents ATM mediated disease and has potent anti-cancer activity.
Para uso exclusivo en investigación. No vendemos a pacientes.
- No. CAS: 2097499-67-5
- Fòrmula: C25H32N6O4S
- Peso molecular:512.62
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
Descripciòn
IC50 & Target
[1]|
ATM |
ATR |
In Vitro
Antitumor agent-28 inhibits ataxia telangiectasia mutated (ATM; IC50=7.6 nM; HT29 cells), ataxia telangiectasia and Rad3-related protein (ATR; IC50=18 μM; HT29 cells), PI3Ka (IC50=0.24 μM; BT474 cells). Antitumor agent-28 does not inhibit mTOR in MDA-MB-468 cells[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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No. CAS 2097499-67-5
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Peso molecular 512.62
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Fòrmula C25H32N6O4S
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SMILES
O=C(N1C(C)C)N(C)C2=C1C3=CC(C4=CC=C(N5CC(N(C)C)C5)N=C4)=CC=C3N=C2.CS(=O)(O)=O
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Antitumor agent-28 Related Classifications
HY-141478 Related Classifications
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