Mcm9 - minichromosome maintenance 9 homologous recombination repair factor Gene

Also Known as Gm235; Mcmdc1; 9030408O17Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 71567

Summary

Enables chromatin binding activity. Involved in DNA repair and female gamete generation. Part of MCM8-MCM9 complex. Is expressed in several structures, including genitourinary system; liver; neural retina; spleen; and telencephalon. Used to study hepatocellular carcinoma. Human ortholog(s) of this gene implicated in ovarian dysgenesis 4. Orthologous to human MCM9 (minichromosome maintenance 9 homologous recombination repair factor). [provided by Alliance of Genome Resources, Apr 2022]

Mcm9 Products (1)

mRNA Protein Name
NM_027830.3 NP_082106.3 DNA helicase MCM9

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables chromatin binding IDA
IDA: Inferred from direct assay
23401855 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
21689717 MGI
Biological Process GO Annotation Evidence References Source
involved in DNA damage response IMP
IMP: Inferred from mutant phenotype
22771120 MGI
NOT involved in DNA replication IMP
IMP: Inferred from mutant phenotype
21987787 MGI
involved in double-strand break repair via homologous recombination IMP
IMP: Inferred from mutant phenotype
22771120 MGI
involved in female gamete generation IMP
IMP: Inferred from mutant phenotype
22771120 MGI
involved in gamete generation IMP
IMP: Inferred from mutant phenotype
21987787 MGI
involved in mismatch repair involved in maintenance of fidelity involved in DNA-dependent DNA replication IMP
IMP: Inferred from mutant phenotype
26300262 MGI
involved in recombinational interstrand cross-link repair IMP
IMP: Inferred from mutant phenotype
23401855 MGI
Cellular Component GO Annotation Evidence References Source
part of MCM8-MCM9 complex IDA
IDA: Inferred from direct assay
22771120 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

DNA helicase MCM9

  • DNA replication licensing factor MCM9

  • mini-chromosome maintenance deficient 9

  • mini-chromosome maintenance deficient domain-containing protein 1

  • minichromosome maintenance complex component 9

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS08242 MCM9 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22232 Mcm9 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28754 Mcm9 Rat Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Mcm9 NCBI NCBI:254394