Ist1 - increased sodium tolerance 1 homolog (yeast) Gene

Also Known as CHMP8; mKIAA0174; 2400003C14Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 71955

Summary

Predicted to enable MIT domain binding activity and identical protein binding activity. Acts upstream of or within positive regulation of collateral sprouting. Predicted to be located in several cellular components, including Flemming body; endoplasmic reticulum-Golgi intermediate compartment; and extracellular exosome. Predicted to colocalize with chromatin. Is expressed in nervous system; sensory organ; submandibular gland primordium; tooth; and vibrissa. Orthologous to human IST1 (IST1 factor associated with ESCRT-III). [provided by Alliance of Genome Resources, Apr 2022]

Ist1 Products (2)

mRNA Protein Name
NM_001361562.1 NP_001348491.1 IST1 homolog isoform 2
NM_028018.2 NP_082294.1 IST1 homolog isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
18209100 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of collateral sprouting IGI
IGI: Inferred from genetic interaction
22619377 MGI
acts upstream of or within positive regulation of collateral sprouting IGI
IGI: Inferred from genetic interaction
22619377 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

IST1 homolog

  • charged multivesicular body protein 8

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS06939 IST1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17370 Ist1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23824 Ist1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ist1 NCBI NCBI:9798