DNLZ - DNL-type zinc finger Gene

Also Known as HEP; HEP1; ZIM17; TIMM15; C9orf151; bA413M3.2

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 728489

About DNLZ

This gene has 2 transcripts (splice variants) and 182 orthologues. Ubiquitous expression in kidney (RPKM 6.4), spleen (RPKM 4.8) and 25 other tissues.

Summary

Predicted to enable chaperone binding activity. Predicted to be involved in protein folding; protein import into mitochondrial matrix; and protein stabilization. Located in mitochondrion and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]

DNLZ Products (1)

mRNA Protein Name
NM_001080849.3 NP_001074318.1 DNL-type zinc finger protein

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein folding chaperone IDA
IDA: Inferred from direct assay
33857516 GOA
Biological Process GO Annotation Evidence References Source
involved in chaperone-mediated protein complex assembly IDA
IDA: Inferred from direct assay
33857516 GOA
Cellular Component GO Annotation Evidence References Source
is active in cytosol IDA
IDA: Inferred from direct assay
33857516 GOA
is active in mitochondrion IDA
IDA: Inferred from direct assay
33857516 GOA
is active in nucleus IDA
IDA: Inferred from direct assay
33857516 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

DNLZ Protein Structure

zf-DNL

zf-DNL: DNL zinc finger (69 - 136)

  • 0
  • 100
  • 178 a.a.
Protein Preferred Names Protein Names

DNL-type zinc finger protein

  • HSP70 escort protein

Related Diseases

Diseases Alias
Spastic Ataxia 5
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS03902 DNLZ Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus DNLZ VGNC VGNC:28141
Canis familiaris DNLZ VGNC VGNC:40031
Rattus norvegicus DNLZ RGD RGD:1308635
Mus musculus DNLZ MGD MGI:106559
Macaca mulatta DNLZ VGNC VGNC:72033
Others DNLZ NCBI