country

Change Language

EN - English
FR - Français
DE - Deutsch
ES - Español
JA - 日本語
KO - 한국어

Country or Region:

United States

Product Name	Size / Unit Price	Qty

Total: USD 0.00 Checkout

TBC1D3 - TBC1 domain family member 3 Gene

Also Known as PRC17; TBC1D3A; TBC1D3C; TBC1D3D; TBC1D3F; TBC1D3L

Species: Homo sapiens

Gene Type: protein coding

Gene ID: 729873

About TBC1D3

Cytogenetic location: 17q12 Genomic coordinates (GRCh38): 17:38,181,659-38,192,555 (from NCBI)

This gene has 1 transcript (splice variant), 21 orthologues and 45 paralogues. Broad expression in testis (RPKM 25.9), skin (RPKM 14.0) and 24 other tissues.

Summary

Predicted to enable GTPase activator activity. Predicted to be involved in activation of GTPase activity and intracellular protein transport. Predicted to be located in early endosome membrane. [provided by Alliance of Genome Resources, Apr 2022]

TBC1D3 Products (1)

mRNA	Protein	Name
NM_001123391.4	NP_001116863.3	TBC1 domain family member 3

Gene Ontology

Biological Process

Biological Process GO Annotation	Evidence	References	Source
NOT involved in regulation of cilium assembly	IMP IMP: Inferred from mutant phenotype	17646400	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

TBC1D3 Protein Structure

RabGAP-TBC

0
100
200
300
400
500
593 a.a.

Protein Preferred Names	Protein Names
TBC1 domain family member 3	Rab GTPase-activating protein PRC17

Related Diseases

Diseases	Alias
Prostate Cancer	Prostate Carcinoma Prostate Cancer, Familial Prostate Neoplasm Prostate Cancer, Somatic Prostate Cancer, Susceptibility To Prostatic Cancer Prostatic Neoplasms Hereditary Prostate Cancer Prostatic Neoplasm Cancer Of Prostate Carcinoma Of Prostate Familial Prostate Cancer Familial Prostate Carcinoma Malignant Tumor Of Prostate Malignant Neoplasm Of Prostate Prostate Cancer, Familial, Susceptibility To Malignant Tumor Of The Prostate Ngp - New Growth Of Prostate Tumor Of The Prostate Prostate Cancer, Hereditary Cancer Of The Prostate Malignant Neoplasm Of The Prostate Prostatic Carcinoma PC Prca Cancer, Prostate Malignant Prostatic Tumour Malignant Tumour Of Prostate Primary Prostate Cancer Primary Malignant Neoplasm Of Prostate Prostate Gland Cancer

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS14241	TBC1D3 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS14243	TBC1D3B Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown