TBC1D3 - TBC1 domain family member 3 Gene

Homo sapiens

Also known as PRC17; TBC1D3A; TBC1D3C; TBC1D3D; TBC1D3F; TBC1D3L

Gene ID: 729873 | Gene type: protein coding

About TBC1D3

Cytogenetic location: 17q12 Genomic coordinates (GRCh38): 17:38,181,659-38,192,555 (from NCBI)

This gene has 1 transcript (splice variant), 21 orthologues and 45 paralogues. Broad expression in testis (RPKM 25.9), skin (RPKM 14.0) and 24 other tissues.

Summary

Predicted to enable GTPase activator activity. Predicted to be involved in activation of GTPase activity and intracellular protein transport. Predicted to be located in early endosome membrane. [provided by Alliance of Genome Resources, Apr 2022]

TBC1D3 Products(1)

mRNA	Protein	Name
NM_001123391.4	NP_001116863.3	TBC1 domain family member 3

TBC1D3 Protein Structure

RabGAP-TBC

0
100
200
300
400
500
593 a.a.

Protein Preferred Names

Protein Names

TBC1 domain family member 3

Rab GTPase-activating protein PRC17

Related Diseases

Diseases

Alias

Prostate Cancer

Prostate Carcinoma	Prostate Cancer, Familial
Prostate Neoplasm	Prostate Cancer, Somatic
Prostate Cancer, Susceptibility To	Prostatic Cancer
Prostatic Neoplasms	Hereditary Prostate Cancer
Prostatic Neoplasm	Cancer Of Prostate
Carcinoma Of Prostate	Familial Prostate Cancer
Familial Prostate Carcinoma	Malignant Tumor Of Prostate
Malignant Neoplasm Of Prostate	Prostate Cancer, Familial, Susceptibility To
Malignant Tumor Of The Prostate	Ngp - New Growth Of Prostate
Tumor Of The Prostate	Prostate Cancer, Hereditary
Cancer Of The Prostate	Malignant Neoplasm Of The Prostate
Prostatic Carcinoma	PC
Prca	Cancer, Prostate
Malignant Prostatic Tumour	Malignant Tumour Of Prostate
Primary Prostate Cancer	Primary Malignant Neoplasm Of Prostate
Prostate Gland Cancer

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (2)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS14241	TBC1D3 Human Pre-designed siRNA Set A		/	Unkown
HY-RS14243	TBC1D3B Human Pre-designed siRNA Set A		/	Unkown

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