Otud4 - OTU domain containing 4 Gene

Also Known as D8Ertd69e; mKIAA1046; 4930431L18Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 73945

Summary

Enables Lys63-specific Deubiquitinase activity. Involved in negative regulation of interleukin-1-mediated signaling pathway; negative regulation of Toll-like Receptor signaling pathway; and protein K63-linked deubiquitination. Predicted to be located in cytosol. Is expressed in several structures, including brain; cardiovascular system; genitourinary system; gut; and immune system. Orthologous to human OTUD4 (OTU Deubiquitinase 4). [provided by Alliance of Genome Resources, Apr 2022]

Otud4 Products (2)

mRNA Protein Name
NM_001081164.1 NP_001074633.1 OTU domain-containing protein 4 isoform 2
NM_001256033.1 NP_001242962.1 OTU domain-containing protein 4 isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables K63-linked deubiquitinase activity IDA
IDA: Inferred from direct assay
29395066 MGI
Biological Process GO Annotation Evidence References Source
involved in negative regulation of interleukin-1-mediated signaling pathway IDA
IDA: Inferred from direct assay
29395066 MGI
involved in negative regulation of toll-like receptor signaling pathway IDA
IDA: Inferred from direct assay
29395066 MGI
involved in protein K63-linked deubiquitination IDA
IDA: Inferred from direct assay
29395066 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

OTU domain-containing protein 4

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-161774 ST80 Inhibitor / Unkown
HY-RS09873 OTUD4 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20073 Otud4 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Otud4 NCBI NCBI:54726