Fcho1 - FCH domain only 1 Gene

Also Known as 3322402E17Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 74015

Summary

Predicted to enable AP-2 adaptor complex binding activity. Predicted to be involved in clathrin coat assembly and clathrin-dependent endocytosis. Predicted to act upstream of or within endocytosis. Predicted to be located in cytosol and nucleoplasm. Predicted to be active in clathrin-coated pit and clathrin-coated vesicle. Is expressed in central nervous system; ganglia; neural retina; and thymus primordium. Human ortholog(s) of this gene implicated in primary immunodeficiency disease. Orthologous to human FCHO1 (FCH and mu domain containing endocytic adaptor 1). [provided by Alliance of Genome Resources, Apr 2022]

Fcho1 Products (1)

mRNA Protein Name
NM_028715.3 NP_082991.3 F-BAR domain only protein 1
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
24130457 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

F-BAR domain only protein 1

Orthologs Information

Species Symbol Source ID
Homo sapiens Fcho1 NCBI NCBI:23149