UTY - ubiquitously transcribed tetratricopeptide repeat containing, Y-linked Gene
Also Known as UTY1; KDM6C; KDM6AL
Species: Homo sapiens
About UTY
This gene has 22 transcripts (splice variants), 148 orthologues and 2 paralogues. Broad expression in prostate (RPKM 1.9), small intestine (RPKM 1.4) and 20 other tissues.
Summary
This gene encodes a protein containing tetratricopeptide repeats which are thought to be involved in protein-protein interactions. The encoded protein is also a minor histocompatibility antigen which may induce graft rejection of male stem cell grafts. A large number of alternatively spliced transcripts have been observed for this gene, but the full length nature of some of these variants has not been determined. [provided by RefSeq, Apr 2012]
UTY Products (39)
| mRNA | Protein | Name |
|---|---|---|
| NM_001258249.2 | NP_001245178.1 | histone demethylase UTY isoform 4 |
| NM_001258250.1 | NP_001245179.1 | histone demethylase UTY isoform 5 |
| NM_001258251.1 | NP_001245180.1 | histone demethylase UTY isoform 6 |
| NM_001258252.1 | NP_001245181.1 | histone demethylase UTY isoform 7 |
| NM_001258253.1 | NP_001245182.1 | histone demethylase UTY isoform 8 |
| NM_001258254.1 | NP_001245183.1 | histone demethylase UTY isoform 9 |
| NM_001258255.1 | NP_001245184.1 | histone demethylase UTY isoform 10 |
| NM_001258256.1 | NP_001245185.1 | histone demethylase UTY isoform 11 |
| NM_001258257.1 | NP_001245186.1 | histone demethylase UTY isoform 12 |
| NM_001258258.1 | NP_001245187.1 | histone demethylase UTY isoform 13 |
| NM_001258259.1 | NP_001245188.1 | histone demethylase UTY isoform 14 |
| NM_001258260.1 | NP_001245189.1 | histone demethylase UTY isoform 15 |
| NM_001258261.1 | NP_001245190.1 | histone demethylase UTY isoform 16 |
| NM_001258262.1 | NP_001245191.1 | histone demethylase UTY isoform 17 |
| NM_001258263.1 | NP_001245192.1 | histone demethylase UTY isoform 18 |
| NM_001258264.1 | NP_001245193.1 | histone demethylase UTY isoform 19 |
| NM_001258265.1 | NP_001245194.1 | histone demethylase UTY isoform 20 |
| NM_001258266.1 | NP_001245195.1 | histone demethylase UTY isoform 21 |
| NM_001258267.1 | NP_001245196.1 | histone demethylase UTY isoform 22 |
| NM_001258268.1 | NP_001245197.1 | histone demethylase UTY isoform 23 |
| NM_001258269.1 | NP_001245198.1 | histone demethylase UTY isoform 24 |
| NM_001258270.1 | NP_001245199.1 | histone demethylase UTY isoform 25 |
| NM_001400170.1 | NP_001387099.1 | histone demethylase UTY isoform 26 |
| NM_001400171.1 | NP_001387100.1 | histone demethylase UTY 27 |
| NM_001400173.1 | NP_001387102.1 | histone demethylase UTY isoform 28 |
| NM_001400175.1 | NP_001387104.1 | histone demethylase UTY isoform 29 |
| NM_001400177.1 | NP_001387106.1 | histone demethylase UTY isoform 30 |
| NM_001400178.1 | NP_001387107.1 | histone demethylase UTY isoform 31 |
| NM_001400181.1 | NP_001387110.1 | histone demethylase UTY isoform 32 |
| NM_001400183.1 | NP_001387112.1 | histone demethylase UTY isoform 33 |
| NM_001400185.1 | NP_001387114.1 | histone demethylase UTY isoform 34 |
| NM_001400187.1 | NP_001387116.1 | histone demethylase UTY isoform 35 |
| NM_001400189.1 | NP_001387118.1 | histone demethylase UTY isoform 36 |
| NM_001400192.1 | NP_001387121.1 | histone demethylase UTY isoform 37 |
| NM_001400195.1 | NP_001387124.1 | histone demethylase UTY isoform 38 |
| NM_001400199.1 | NP_001387128.1 | histone demethylase UTY isoform 39 |
| NM_007125.4 | NP_009056.3 | histone demethylase UTY isoform 3 |
| NM_182659.1 | NP_872600.1 | histone demethylase UTY isoform 2 |
| NM_182660.1 | NP_872601.1 | histone demethylase UTY isoform 1 |
UTY Protein Structure
TPR_1: Tetratricopeptide repeat (127 - 160)
TPR_8: Tetratricopeptide repeat (204 - 230)
TPR_17: Tetratricopeptide repeat (270 - 300)
TPR_11: TPR repeat (315 - 375)
JmjC: JmjC domain, hydroxylase (1080 - 1188)
- 0
- 300
- 600
- 900
- 1200
- 1347 a.a.
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
histone demethylase UTY |
|
Related Agents
- Pre-clinical Phase
Pre-clinical Phase
| Cat. No. | Product Name |
Effect
|
Purity |
Rare Diseases
|
|---|---|---|---|---|
| HY-RS15587 | UTY Human Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS17629 | Uty Mouse Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS24089 | Uty Rat Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
Orthologs Information
| Species | Symbol | Source | ID |
|---|---|---|---|
| Macaca mulatta | UTY | VGNC | VGNC:101433 |
| Rattus norvegicus | UTY | RGD | RGD:1565481 |
| Mus musculus | UTY | MGD | MGI:894810 |
| Others | UTY | NCBI |
Compound Screening Libraries
Virtual Screening
Customize Your Library
Drug Screening Service