Ckap5 - cytoskeleton associated protein 5 Gene

Also Known as mKIAA0097; 3110043H24Rik; 4930432B04Rik; D730027C18Rik

Species: Mus musculus

Gene Type: protein coding

Gene ID: 75786

Summary

Predicted to enable microtubule binding activity; microtubule plus end polymerase; and ribonucleoprotein complex binding activity. Acts upstream of or within several processes, including central nervous system myelin formation; dendritic spine maintenance; and learning. Located in dendrite; neuronal ribonucleoprotein granule; and perikaryon. Is expressed in several structures, including nervous system; nose; respiratory system; thymus primordium; and tooth. Orthologous to human CKAP5 (Cytoskeleton associated protein 5). [provided by Alliance of Genome Resources, Apr 2022]

Ckap5 Products (2)

mRNA	Protein	Name
NM_001165989.2	NP_001159461.1	cytoskeleton-associated protein 5 isoform 1
NM_029437.2	NP_083713.2	cytoskeleton-associated protein 5 isoform 2

Gene Ontology

Biological Process
Cellular Component

Biological Process GO Annotation	Evidence	References	Source
acts upstream of or within central nervous system myelin formation	IMP IMP: Inferred from mutant phenotype	28063167	MGI
acts upstream of cytoplasmic translation	IDA IDA: Inferred from direct assay	23936366	MGI
acts upstream of or within cytoplasmic translation	IMP IMP: Inferred from mutant phenotype	23936366	MGI
acts upstream of or within dendritic spine maintenance	IMP IMP: Inferred from mutant phenotype	23936366	MGI
acts upstream of or within excitatory postsynaptic potential	IMP IMP: Inferred from mutant phenotype	23936366	MGI
acts upstream of or within habituation	IMP IMP: Inferred from mutant phenotype	23936366	MGI
acts upstream of or within locomotory behavior	IMP IMP: Inferred from mutant phenotype	28063167	MGI
acts upstream of or within long-term synaptic potentiation	IMP IMP: Inferred from mutant phenotype	23936366	MGI
acts upstream of or within mRNA localization resulting in post-transcriptional regulation of gene expression	IMP IMP: Inferred from mutant phenotype	28063167	MGI
acts upstream of or within positive regulation of endocytosis	IMP IMP: Inferred from mutant phenotype	23936366	MGI
acts upstream of or within protein-RNA complex assembly	IDA IDA: Inferred from direct assay	23936366	MGI
acts upstream of or within protein-RNA complex assembly	IMP IMP: Inferred from mutant phenotype	23936366	MGI
acts upstream of or within visual learning	IMP IMP: Inferred from mutant phenotype	23936366	MGI

Cellular Component GO Annotation	Evidence	References	Source
located in dendrite	IDA IDA: Inferred from direct assay	23936366	MGI
located in neuronal ribonucleoprotein granule	IDA IDA: Inferred from direct assay	23936366	MGI
located in perikaryon	IDA IDA: Inferred from direct assay	23936366	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names	Protein Names
cytoskeleton-associated protein 5

Related Agents

Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS02735	CKAP5 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS20378	Ckap5 Mouse Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS26888	Ckap5 Rat Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Ckap5	NCBI	NCBI:9793