Kansl1 - KAT8 regulatory NSL complex subunit 1 Gene

Also Known as mKIAA1267; 1700081L11Rik; 9430041J06Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 76719

Summary

Predicted to enable Histone Acetyltransferase binding activity. Predicted to be involved in histone H4-K16 acetylation; histone H4-K5 acetylation; and histone H4-K8 acetylation. Predicted to act upstream of or within chromatin organization. Predicted to be located in nucleoplasm. Predicted to be part of MLL1 complex and NSL complex. Is expressed in brain. Human ortholog(s) of this gene implicated in Koolen de Vries syndrome. Orthologous to human KANSL1 (KAT8 regulatory NSL complex subunit 1). [provided by Alliance of Genome Resources, Apr 2022]

Kansl1 Products (5)

mRNA Protein Name
NM_001081045.2 NP_001074514.1 KAT8 regulatory NSL complex subunit 1 isoform 1
NM_001359634.1 NP_001346563.1 KAT8 regulatory NSL complex subunit 1 isoform 1
NM_001372458.1 NP_001359387.1 KAT8 regulatory NSL complex subunit 1 isoform 2
NM_001372459.1 NP_001359388.1 KAT8 regulatory NSL complex subunit 1 isoform 3
NM_001372460.1 NP_001359389.1 KAT8 regulatory NSL complex subunit 1 isoform 4

Gene Ontology

  • Cellular Component
Cellular Component GO Annotation Evidence References Source
part of NSL complex IDA
IDA: Inferred from direct assay
24842875 MGI
is active in mitochondrion IDA
IDA: Inferred from direct assay
37813994 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

KAT8 regulatory NSL complex subunit 1

  • NSL complex protein NSL1

  • non-specific lethal 1 homolog

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS07067 KANSL1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20558 Kansl1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27067 Kansl1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Kansl1 NCBI NCBI:284058