ZNF142 - zinc finger protein 142 Gene

Also Known as HA4654; pHZ-49; NEDISHM

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 7701

About ZNF142

Cytogenetic location: 2q35 Genomic coordinates (GRCh38): 2:218,633,329-218,659,623 (from NCBI)

This gene has 6 transcripts (splice variants), 136 orthologues, 36 paralogues and is associated with 2 phenotypes. Ubiquitous expression in brain (RPKM 3.6), testis (RPKM 3.6) and 25 other tissues.

Summary

The protein encoded by this gene belongs to the Kruppel family of C2H2-type zinc finger proteins. It contains 31 C2H2-type zinc fingers and may be involved in transcriptional regulation. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2013]

ZNF142 Products (14)

mRNA Protein Name
NM_001105537.4 NP_001099007.1 zinc finger protein 142 isoform 1
NM_001366287.2 NP_001353216.1 zinc finger protein 142 isoform 2
NM_001366288.2 NP_001353217.1 zinc finger protein 142 isoform 2
NM_001366289.2 NP_001353218.1 zinc finger protein 142 isoform 2
NM_001366290.3 NP_001353219.1 zinc finger protein 142 isoform 3
NM_001366291.2 NP_001353220.1 zinc finger protein 142 isoform 1
NM_001367339.1 NP_001354268.1 zinc finger protein 142 isoform 4
NM_001367340.1 NP_001354269.1 zinc finger protein 142 isoform 4
NM_001367341.1 NP_001354270.1 zinc finger protein 142 isoform 4
NM_001367342.1 NP_001354271.1 zinc finger protein 142 isoform 4
NM_001379659.1 NP_001366588.1 zinc finger protein 142 isoform 3
NM_001379660.1 NP_001366589.1 zinc finger protein 142 isoform 3
NM_001379661.1 NP_001366590.1 zinc finger protein 142 isoform 3
NM_001379662.1 NP_001366591.1 zinc finger protein 142 isoform 1

ZNF142 Protein Structure

zf-C2H2

zf-C2H2: Zinc finger, C2H2 type (192 - 211)

zf-C2H2_4

zf-C2H2_4: C2H2-type zinc finger (253 - 275)

zf-H2C2_2

zf-H2C2_2: Zinc-finger double domain (416 - 437)

zf-C2H2

zf-C2H2: Zinc finger, C2H2 type (457 - 479)

zf-C2H2_4

zf-C2H2_4: C2H2-type zinc finger (514 - 536)

zf-H2C2_5

zf-H2C2_5: C2H2-type zinc-finger domain (836 - 857)

zf-C2H2_4

zf-C2H2_4: C2H2-type zinc finger (868 - 887)

zf-H2C2_5

zf-H2C2_5: C2H2-type zinc-finger domain (1136 - 1159)

zf-H2C2_2

zf-H2C2_2: Zinc-finger double domain (1187 - 1210)

zf-C2H2_4

zf-C2H2_4: C2H2-type zinc finger (1229 - 1251)

zf-C2H2_4

zf-C2H2_4: C2H2-type zinc finger (1286 - 1309)

zf-H2C2_5

zf-H2C2_5: C2H2-type zinc-finger domain (1380 - 1403)

zf-H2C2_2

zf-H2C2_2: Zinc-finger double domain (1469 - 1489)

zf-H2C2_2

zf-H2C2_2: Zinc-finger double domain (1495 - 1518)

zf-H2C2_2

zf-H2C2_2: Zinc-finger double domain (1523 - 1545)

zf-C2H2

zf-C2H2: Zinc finger, C2H2 type (1565 - 1587)

  • 0
  • 300
  • 600
  • 900
  • 1200
  • 1500
  • 1687 a.a.
Protein Preferred Names Protein Names

zinc finger protein 142

  • zinc finger protein 142 (clone pHZ-49)

Related Diseases

Diseases Alias
Neurodevelopmental Disorder With Impaired Speech And Hyperkinetic Movements

  • NEDISHM
Pancreatic Squamous Cell Carcinoma
Generalized Epilepsy With Febrile Seizures Plus, Type 7

  • Febrile Seizures, Familial, 3b

  • GEFSP7

  • GEFS+7

  • Generalized Epilepsy With Febrile Seizures Plus 7

  • Gefs+, Type 7

  • Generalised Epilepsy With Febrile Seizures Plus 7

  • Generalised Epilepsy With Febrile Seizures Plus Type 7

  • Generalized Epilepsy With Febrile Seizures Plus Type 7

  • FEB3B

  • Familial Febrile Convulsions 3

  • Gefs+ Type 7

  • Epilepsy, Generalized, With Febrile Seizures Plus, Type 7

  • Generalized Epilepsy With Febrile Seizures Plus, 7
Dystonia

  • Dystonic Disease

  • Dystonic Disorder

  • Dystonia Disorders

  • Neuroleptic Dyskinesia
Spastic Paraplegia 48, Autosomal Recessive

  • SPG48

  • Hereditary Spastic Paraplegia 48

  • Autosomal Recessive Spastic Paraplegia Type 48

  • Autosomal Recessive Spastic Paraplegia 48

  • Paraplegia, Spastic, Type 48, Autosomal Recessive
Cerebral Creatine Deficiency Syndrome

  • Deficiency, Cerebral Creatine, Syndrome
Cockayne Syndrome A

  • Cockayne Syndrome Type 1

  • Cockayne Syndrome, Type A

  • Cockayne Syndrome Type I

  • CSA

  • Cockayne Syndrome Classic Form

  • Cockayne Syndrome Classical

  • Cockayne Syndrome Type A

  • Ckn1
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS16102 ZNF142 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus ZNF142 RGD RGD:1309648
Mus musculus ZNF142 MGD MGI:1924514
Macaca mulatta ZNF142 VGNC VGNC:78844
Canis familiaris ZNF142 VGNC VGNC:48660
Bos taurus ZNF142 VGNC VGNC:37211
Others ZNF142 NCBI