Skap1 - src family associated phosphoprotein 1 Gene

Also Known as Scap1; Skap-55; 1700091G21Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 78473

Summary

Predicted to enable SH2 domain binding activity; protein kinase binding activity; and protein Phosphatase binding activity. Acts upstream of or within positive regulation of cell adhesion and protein localization to plasma membrane. Located in cell-cell junction; cytosol; and plasma membrane. Part of T cell receptor complex. Orthologous to human SKAP1 (Src kinase associated phosphoprotein 1). [provided by Alliance of Genome Resources, Apr 2022]

Skap1 Products (3)

mRNA Protein Name
NM_001033186.3 NP_001028358.1 src kinase-associated phosphoprotein 1 isoform 1
NM_001177898.1 NP_001171369.1 src kinase-associated phosphoprotein 1 isoform 2
NM_001177899.1 NP_001171370.1 src kinase-associated phosphoprotein 1 isoform 3

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Références Source
enables protein binding IPI
IPI: Inferred from physical interaction
17403904 MGI
Biological Process GO Annotation Evidence Références Source
acts upstream of or within positive regulation of cell adhesion IMP
IMP: Inferred from mutant phenotype
17403904 MGI
acts upstream of or within protein localization to plasma membrane IMP
IMP: Inferred from mutant phenotype
17403904 MGI
Cellular Component GO Annotation Evidence Références Source
part of T cell receptor complex IDA
IDA: Inferred from direct assay
17403904 MGI
located in cell-cell junction IDA
IDA: Inferred from direct assay
23793062 MGI
located in cytosol IDA
IDA: Inferred from direct assay
17403904 MGI
located in plasma membrane IDA
IDA: Inferred from direct assay
17403904 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

src kinase-associated phosphoprotein 1

  • ortholog of human src family associated phosphoprotein 1 SCAP1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Nom du produit
Effect
Pureté
Rare Diseases
HY-RS12967 SKAP1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22805 Skap1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS29320 Skap1 Rat Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Skap1 NCBI NCBI:8631