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  3. GALNT14 - polypeptide N-acetylgalactosaminyltransferase 14 Gene

GALNT14 - polypeptide N-acetylgalactosaminyltransferase 14 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as GALNT15; GalNac-T10; GalNac-T14

Gene ID: 79623 | Gene type: protein coding

About GALNT14

Cytogenetic location: 2p23.1 Genomic coordinates (GRCh38): 2:30,886,782-31,138,440 (from NCBI)

This gene has 15 transcripts (splice variants), 215 orthologues and 19 paralogues. Biased expression in kidney (RPKM 5.0), esophagus (RPKM 0.7) and 7 other tissues.

Summary

This gene encodes a Golgi protein which is a member of the polypeptide N-acetylgalactosaminyltransferase (ppGalNAc-Ts) protein family. These enzymes catalyze the transfer of N-acetyl-D-galactosamine (GalNAc) to the hydroxyl groups on serines and threonines in target Peptides. The encoded protein has been shown to transfer GalNAc to large proteins like mucins. Alterations in this gene may play a role in Cancer progression and response to chemotherapy. [provided by RefSeq, Jun 2016]

GALNT14 Products(6)

mRNA Protein Name
NM_001253826.2 NP_001240755.1 polypeptide N-acetylgalactosaminyltransferase 14 isoform 2
NM_001253827.2 NP_001240756.1 polypeptide N-acetylgalactosaminyltransferase 14 isoform 3
NM_001329095.2 NP_001316024.1 polypeptide N-acetylgalactosaminyltransferase 14 isoform 4
NM_001329096.2 NP_001316025.1 polypeptide N-acetylgalactosaminyltransferase 14 isoform 3
NM_001329097.2 NP_001316026.1 polypeptide N-acetylgalactosaminyltransferase 14 isoform 6
NM_024572.4 NP_078848.2 polypeptide N-acetylgalactosaminyltransferase 14 isoform 1

GALNT14 Protein Structure

Glycos_transf_2

Glycos_transf_2: Glycosyl transferase family 2 (114 - 268)

Glyco_transf_7C

Glyco_transf_7C: N-terminal domain of galactosyltransferase (278 - 336)

Ricin_B_lectin

Ricin_B_lectin: Ricin-type beta-trefoil lectin domain (424 - 547)

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  • 552 a.a.
Protein Preferred Names Protein Names

polypeptide N-acetylgalactosaminyltransferase 14

UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 14

Recombinant GALNT14 Proteins

Cat. No. Product Name Accession Purity
HY-P79352 GALNT14 Protein, Human (CHO, His) Q96FL9 (T27-S552) ≥95%

Related Diseases

Diseases Alias
Hydrops Fetalis, Nonimmune

Hydrops Fetalis

Non-Immune Hydrops Fetalis

NIHF

Familial Non-Immune Hydrops Fetalis

Hydrops Fetalis Nonimmune

Idiopathic Hydrops Fetalis

Hb Bart'S Hydrops Fetalis

Alpha-Thalassemia Hydrops Fetalis

Alpha-Thalassemia Major

Hemoglobin Bart'S Hydrops Fetalis

Homozygous Alpha0-Thalassemia

Fetal Anasarca

Fetal Hydrops

Generalized Fetal Edema

Hf

Non-Immune Hf

Non-Immune Fetal Edema

Non-Immune Fetal Hydrops

Hydrops Fetalis, Non-Immune

Hemoglobin Bart'S Hydrops Syndrome
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS05252 GALNT14 Human Pre-designed siRNA Set A / Unkown
HY-E70295 N-Acetylgalactosaminyltransferase 14 / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus GALNT14 MGD MGI:1918935
Canis familiaris GALNT14 VGNC VGNC:41089
Bos taurus GALNT14 VGNC VGNC:29227
Rattus norvegicus GALNT14 RGD RGD:1310068
Felis catus GALNT14 VGNC VGNC:62446
Macaca mulatta GALNT14 VGNC VGNC:72764