TUT7 - terminal uridylyl transferase 7 Gene

Also Known as PAPD6; TENT3B; ZCCHC6

Species: Homo sapiens

Gene Type: protein coding

Gene ID: 79670

About TUT7

Cytogenetic location: 9q21.33 Genomic coordinates (GRCh38): 9:86,287,733-86,354,410 (from NCBI)

This gene has 7 transcripts (splice variants), 259 orthologues and 4 paralogues. Ubiquitous expression in prostate (RPKM 7.8), skin (RPKM 6.8) and 25 other tissues.

Summary

Enables RNA uridylyltransferase activity and miRNA binding activity. Involved in RNA metabolic process and negative regulation of transposition, RNA-mediated. Located in cytosol and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]

TUT7 Products (4)

mRNA	Protein	Name
NM_001185059.2	NP_001171988.1	terminal uridylyltransferase 7 isoform 1
NM_001185074.2	NP_001172003.1	terminal uridylyltransferase 7 isoform 2
NM_001330718.2	NP_001317647.1	terminal uridylyltransferase 7 isoform 3
NM_024617.4	NP_078893.2	terminal uridylyltransferase 7 isoform 1

TUT7 Protein Structure

PAP_assoc

zf-CCHC

PAP_assoc

zf-CCHC

0
300
600
900
1200
1495 a.a.

Protein Preferred Names	Protein Names
terminal uridylyltransferase 7	PAP associated domain containing 6

Related Diseases

Diseases	Alias
Renal Wilms' Tumor	Nonanaplastic Renal Wilm'S Tumor Nonanaplastic Renal Wilm'S Tumour Nonanaplastic Renal Wilms Tumor Renal Wilms' Tumour
Perlman Syndrome	Nephroblastomatosis, Fetal Ascites, Macrosomia And Wilms Tumor PRLMNS Renal Hamartomas, Nephroblastomatosis, And Fetal Gigantism Nephroblastomatosis Fetal Ascites Macrosomia And Wilms Tumor Nephroblastomatosis, Fetal Ascites, Macrosomia, And Wilms Tumor Nephroblastomatosis - Fetal Ascites - Macrosomia - Wilms Tumor Renal Hamartomas, Nephroblastomatosis And Fetal Gigantism Nephroblastomatosis-Fetal Ascites-Macrosomia-Wilms Tumor Syndrome Renal Hamartomas Nephroblastomatosis And Fetal Gigantism Nephroblastoma Fetal Macrosomia
Spastic Ataxia 4
Treacher Collins Syndrome 1	Treacher Collins Syndrome Mandibulofacial Dysostosis Treacher Collins-Franceschetti Syndrome Tcof Tcs Mfd1 Franceschetti-Klein Syndrome TCS1 Franceschetti Syndrome Franceschetti-Zwahlen-Klein Syndrome Zygoauromandibular Dysplasia Treacher-Collins Syndrome Mandibulofacial Dysostosis Without Limb Anomalies Bilateral And Symmetric Oto-Mandibular Dysplasia
Wilms Tumor 1	Nephroblastoma Wilms Tumor WT1 Wilms' Tumor Bilateral Wilms Tumor Wilms Tumor, Type 1 Wilms Tumor, Somatic Adult Nephroblastoma Wt1 Disorder Renal Embryonic Tumor Adult Kidney Wilms Tumor Childhood Kidney Wilms Tumor Nonanaplastic Kidney Wilms Tumor

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-169090	TS-002902	Inhibitor	98.29%	Unkown
HY-RS15278	TUT7 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Felis catus	TUT7	VGNC	VGNC:66715
Mus musculus	TUT7	MGD	MGI:2387179
Canis familiaris	TUT7	VGNC	VGNC:48571
Rattus norvegicus	TUT7	RGD	RGD:1586015
Macaca mulatta	TUT7	VGNC	VGNC:79545
Bos taurus	TUT7	VGNC	VGNC:37121
Others	TUT7	NCBI