MCTP1 - multiple C2 and transmembrane domain containing 1 Gene
Species: Homo sapiens
Gene Type: protein coding
Gene ID: 79772
About MCTP1
Cytogenetic location: 5q15
Genomic coordinates (GRCh38): 5:94,703,690-95,285,094 (from NCBI)
This gene has 18 transcripts (splice variants), 270 orthologues and 1 paralogue. Ubiquitous expression in brain (RPKM 4.3), fat (RPKM 3.5) and 22 other tissues.
Summary
Enables calcium ion binding activity. Predicted to be involved in several processes, including modulation of chemical synaptic transmission; negative regulation of endocytosis; and negative regulation of response to oxidative stress. Is integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022]
MCTP1 Products (20)
| mRNA | Protein | Name |
|---|---|---|
| NM_001002796.5 | NP_001002796.1 | multiple C2 and transmembrane domain-containing protein 1 isoform S |
| NM_001297777.3 | NP_001284706.1 | multiple C2 and transmembrane domain-containing protein 1 isoform 3 |
| NM_001393535.1 | NP_001380464.1 | multiple C2 and transmembrane domain-containing protein 1 isoform 4 |
| NM_001393536.1 | NP_001380465.1 | multiple C2 and transmembrane domain-containing protein 1 isoform 5 |
| NM_001393537.1 | NP_001380466.1 | multiple C2 and transmembrane domain-containing protein 1 isoform 6 |
| NM_001393538.1 | NP_001380467.1 | multiple C2 and transmembrane domain-containing protein 1 isoform 7 |
| NM_001393539.1 | NP_001380468.1 | multiple C2 and transmembrane domain-containing protein 1 isoform 8 |
| NM_001393540.1 | NP_001380469.1 | multiple C2 and transmembrane domain-containing protein 1 isoform 9 |
| NM_001393541.1 | NP_001380470.1 | multiple C2 and transmembrane domain-containing protein 1 isoform 10 |
| NM_001393542.1 | NP_001380471.1 | multiple C2 and transmembrane domain-containing protein 1 isoform 11 |
| NM_001393543.1 | NP_001380472.1 | multiple C2 and transmembrane domain-containing protein 1 isoform 12 |
| NM_001393544.1 | NP_001380473.1 | multiple C2 and transmembrane domain-containing protein 1 isoform 13 |
| NM_001393545.1 | NP_001380474.1 | multiple C2 and transmembrane domain-containing protein 1 isoform 14 |
| NM_001393546.1 | NP_001380475.1 | multiple C2 and transmembrane domain-containing protein 1 isoform 15 |
| NM_001393547.1 | NP_001380476.1 | multiple C2 and transmembrane domain-containing protein 1 isoform 16 |
| NM_001393548.1 | NP_001380477.1 | multiple C2 and transmembrane domain-containing protein 1 isoform 17 |
| NM_001393549.1 | NP_001380478.1 | multiple C2 and transmembrane domain-containing protein 1 isoform 18 |
| NM_001393550.1 | NP_001380479.1 | multiple C2 and transmembrane domain-containing protein 1 isoform 19 |
| NM_001393551.1 | NP_001380480.1 | multiple C2 and transmembrane domain-containing protein 1 isoform 20 |
| NM_024717.7 | NP_078993.4 | multiple C2 and transmembrane domain-containing protein 1 isoform L |
| Molecular Function GO Annotation | Evidence | References | Source |
|---|---|---|---|
| enables calcium ion binding |
IDA
IDA: Inferred from direct assay
|
15528213 | GOA |
| NOT enables calcium-dependent phospholipid binding |
IDA
IDA: Inferred from direct assay
|
15528213 | GOA |
| Cellular Component GO Annotation | Evidence | References | Source |
|---|---|---|---|
| located in membrane |
IDA
IDA: Inferred from direct assay
|
15528213 | GOA |
EXP: Inferred from Experiment
IDA: Inferred from direct assay
IPI: Inferred from physical interaction
IMP: Inferred from mutant phenotype
IGI: Inferred from genetic interaction
IEP: Inferred from expression pattern
MCTP1 Protein Structure
C2
C2: C2 domain (263 - 343)
C2
C2: C2 domain (473 - 553)
C2
C2: C2 domain (628 - 707)
PRT_C
PRT_C: Plant phosphoribosyltransferase C-terminal (872 - 974)
- 0
- 200
- 400
- 600
- 800
- 999 a.a.
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
multiple C2 and transmembrane domain-containing protein 1 |
|
Related Agents
- Pre-clinical Phase
Pre-clinical Phase
Bioactive Molecules
(1)
| Cat. No. | Product Name |
Effect
|
Purity |
Rare Diseases
|
|---|---|---|---|---|
| HY-RS08249 | MCTP1 Human Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
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