ZBTB3 - zinc finger and BTB domain containing 3 Gene

Species: Homo sapiens

Gene Type: protein coding

Gene ID: 79842

About ZBTB3

This gene has 4 transcripts (splice variants), 185 orthologues and 28 paralogues. Ubiquitous expression in testis (RPKM 1.5), skin (RPKM 1.4) and 25 other tissues.

Summary

Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2022]

ZBTB3 Products (3)

mRNA	Protein	Name
NM_001363108.2	NP_001350037.1	zinc finger and BTB domain-containing protein 3
NM_001363109.2	NP_001350038.1	zinc finger and BTB domain-containing protein 3
NM_001370809.1	NP_001357738.1	zinc finger and BTB domain-containing protein 3

Gene Ontology

Molecular Function

Molecular Function GO Annotation	Evidence	References	Source
enables protein binding	IPI IPI: Inferred from physical interaction	32296183	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

ZBTB3 Protein Structure

BTB

zf-H2C2_2

0
100
200
300
400
500
574 a.a.

Protein Preferred Names	Protein Names
zinc finger and BTB domain-containing protein 3

Related Agents

Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS15970	ZBTB3 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Rattus norvegicus	ZBTB3	RGD	RGD:1561140
Macaca mulatta	ZBTB3	VGNC	VGNC:107666
Felis catus	ZBTB3	VGNC	VGNC:104348
Mus musculus	ZBTB3	MGD	MGI:1922541
Canis familiaris	ZBTB3	VGNC	VGNC:48530
Bos taurus	ZBTB3	VGNC	VGNC:37071
Others	ZBTB3	NCBI