WDR76 - WD repeat domain 76 Gene

Also Known as CDW14

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 79968

About WDR76

This gene has 4 transcripts (splice variants) and 198 orthologues. Broad expression in lymph node (RPKM 6.6), bone marrow (RPKM 3.7) and 23 other tissues.

Summary

Enables enzyme binding activity. Involved in cellular response to DNA damage stimulus. Located in heterochromatin; nucleus; and site of DNA damage. [provided by Alliance of Genome Resources, Apr 2022]

WDR76 Products (2)

mRNA Protein Name
NM_001167941.2 NP_001161413.1 WD repeat-containing protein 76 isoform 2
NM_024908.4 NP_079184.2 WD repeat-containing protein 76 isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables enzyme binding IPI
IPI: Inferred from physical interaction
27248496 GOA
enables protein binding IPI
IPI: Inferred from physical interaction
27248496 GOA
Biological Process GO Annotation Evidence References Source
involved in DNA damage response IMP
IMP: Inferred from mutant phenotype
27248496 GOA
Cellular Component GO Annotation Evidence References Source
located in heterochromatin IMP
IMP: Inferred from mutant phenotype
27248496 GOA
located in nucleus IDA
IDA: Inferred from direct assay
27248496 GOA
located in site of DNA damage IMP
IMP: Inferred from mutant phenotype
27248496 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

WDR76 Protein Structure

WD40

WD40: WD domain, G-beta repeat (353 - 386)

WD40

WD40: WD domain, G-beta repeat (486 - 524)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 500
  • 626 a.a.
Protein Preferred Names Protein Names

WD repeat-containing protein 76

Related Diseases

Diseases Alias
Congenital Disorder Of Glycosylation, Type Ig

  • CDG1G

  • Alg12-Congenital Disorder Of Glycosylation

  • Cdg Ig

  • Congenital Disorder Of Glycosylation Type 1g

  • Congenital Disorder Of Glycosylation Type Ig

  • Cdgig

  • Congenital Disorder Of Glycosylation Ig

  • Congenital Disorder Of Glycosylation 1g

  • Cdg-Ig

  • Alg12-Cdg

  • Cdg Syndrome Type Ig

  • Carbohydrate Deficient Glycoprotein Syndrome Type Ig

  • Mannosyltransferase 8 Deficiency

  • Glycosylation, Congenital Disorder Of, Type Ig
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS15797 WDR76 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus WDR76 RGD RGD:1309616
Felis catus WDR76 VGNC VGNC:67055
Bos taurus WDR76 VGNC VGNC:36920
Canis familiaris WDR76 VGNC VGNC:48388
Macaca mulatta WDR76 VGNC VGNC:79542
Mus musculus WDR76 MGD MGI:1926186
Others WDR76 NCBI