CAMK4 - calcium/calmodulin dependent protein kinase IV Gene

Homo sapiens

Also known as caMK; CaMKIV; CaMK IV; CaMK-GR

Gene ID: 814 | Gene type: protein coding

About CAMK4

Cytogenetic location: 5q22.1 Genomic coordinates (GRCh38): 5:111,223,583-111,494,886 (from NCBI)

This gene has 13 transcripts (splice variants), 173 orthologues and 6 paralogues. Broad expression in brain (RPKM 7.0), lymph node (RPKM 3.7) and 21 other tissues.

Summary

The product of this gene belongs to the serine/threonine protein kinase family, and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. This Enzyme is a multifunctional serine/threonine protein kinase with limited tissue distribution, that has been implicated in transcriptional regulation in lymphocytes, neurons and male germ cells. [provided by RefSeq, Jul 2008]

CAMK4 Products(5)

mRNA	Protein	Name
NM_001323374.2	NP_001310303.1	calcium/calmodulin-dependent protein kinase type IV isoform 1
NM_001323375.2	NP_001310304.1	calcium/calmodulin-dependent protein kinase type IV isoform 1
NM_001323376.2	NP_001310305.1	calcium/calmodulin-dependent protein kinase type IV isoform 2
NM_001323377.2	NP_001310306.1	calcium/calmodulin-dependent protein kinase type IV isoform 2
NM_001744.6	NP_001735.1	calcium/calmodulin-dependent protein kinase type IV isoform 1

CAMK4 Protein Structure

Pkinase

0
100
200
300
400
473 a.a.

Protein Preferred Names

Protein Names

calcium/calmodulin-dependent protein kinase type IV

CAM kinase IV

Recombinant CAMK4 Proteins

Cat. No.	Product Name	Accession	Purity
HY-P75458	CAMKIV/CAMK4 Protein, Human (HEK293, GST)	NP_001735.1 (M1-Y473)	≥95%

Related Diseases

Diseases

Alias

Cerebral Hypoxia

Brain Hypoxia

Autism

Autistic Disorder	Autism Susceptibility 1
Childhood Autism	Autistic Disorder Of Childhood Onset
Infantile Autism	Kanner'S Syndrome
Autistic

Fragile X Syndrome

FXS	Martin-Bell Syndrome
Fraxa Syndrome	Marker X Syndrome
X-Linked Mental Retardation And Macroorchidism	Fragile X Mental Retardation Syndrome
Fra Syndrome	Mental Retardation, X-Linked, Associated With Marxq28
X-Linked Intellectual Disability And Macroorchidism	Frax Syndrome
Symptomatic Form Of Fragile X Syndrome In Female Carriers	Fragile-X Syndrome
Fraxe Syndrome

Alcohol Dependence

Alcoholism	Alcohol Dependence, Susceptibility To
Alcohol Dependence, Protection Against	Aerodigestive Tract Cancer, Squamous Cell, Alcohol-Related, Protection Against
Alcoholism, Susceptibility To	Alcoholic Intoxication, Chronic
Pharyngeal Neoplasms	Chronic Alcoholism
Dipsomania	Alcohol Addiction
Ethanol Dependence	Chronic Ethanolism
Chronic Alcoholic Disease Nos	Alcoholic Disease Nos
Alcoholic

Systemic Lupus Erythematosus

Lupus Nephritis	SLE
Disseminated Lupus Erythematosus	Systemic Lupus Erythematosus, Susceptibility To
Lupus Erythematosus, Systemic	Lupus Nephritis, Susceptibility To
Libman-Sacks Disease	Systemic Lupus Erythematosus Susceptibility To
Sle - Lupus Erythematosus, Systemic	Le Syndrome
Lupus	Lupus Erythematosus Systemic
Lupus Erythematosus, Systemic, Susceptibility To	Lupus Vulgaris
Lupus Erythematosus, Discoid	Lupus Erythematosus
Systemic Lupus Erythematosus Nos	Sle - [Systemic Lupus Erythematosus]

Autism Spectrum Disorder

Asd	Autism Spectrum Disorders
Autistic Continuum	Pervasive Developmental Disorder
Pervasive Development Disorder	Autistic Behavior
Autistic Disorder	Autistic
Autistic Disorder Of Childhood Onset	Infantile Autism
Childhood Autism	Kanner Syndrome
Pervasive Developmental Delay Nos	Pervasive Developmental Disorder, Not Otherwise Specified

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS01864	CAMK4 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Rattus norvegicus	CAMK4	RGD	RGD:2264
Bos taurus	CAMK4	VGNC	VGNC:106668
Canis familiaris	CAMK4	VGNC	VGNC:53157
Felis catus	CAMK4	VGNC	VGNC:60335
Macaca mulatta	CAMK4	VGNC	VGNC:70526
Mus musculus	CAMK4	MGD	MGI:88258
Others	CAMK4	NCBI

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