Nell1 - neural EGFL like 1 Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 81733

Summary

Enables heparin binding activity; identical protein binding activity; and protein kinase C binding activity. Involved in positive regulation of apoptotic process; positive regulation of ossification; and regulation of osteoblast differentiation. Located in cytoplasm and extracellular space. Used to study craniosynostosis. Orthologous to human NELL1 (neural EGFL like 1). [provided by Alliance of Genome Resources, Apr 2022]

Nell1 Products (1)

mRNA Protein Name
NM_031069.2 NP_112331.2 protein kinase C-binding protein NELL1 precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables heparin binding IDA
IDA: Inferred from direct assay
10548494 RGD
enables identical protein binding IPI
IPI: Inferred from physical interaction
10548494 RGD
enables protein kinase C binding IDA
IDA: Inferred from direct assay
10600492 RGD
Biological Process GO Annotation Evidence References Source
involved in positive regulation of apoptotic process IDA
IDA: Inferred from direct assay
14672347 RGD
involved in positive regulation of ossification IMP
IMP: Inferred from mutant phenotype
19493425 RGD
involved in regulation of osteoblast differentiation IMP
IMP: Inferred from mutant phenotype
12235118 RGD
Cellular Component GO Annotation Evidence References Source
located in extracellular space IDA
IDA: Inferred from direct assay
10548494 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

protein kinase C-binding protein NELL1

  • NEL-like 1

  • NEL-like protein 1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS09204 NELL1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20453 Nell1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26962 Nell1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Nell1 NCBI NCBI:4745